BDBM50145277 1-{4-[(9-Fluoro-5,6-dihydro-4H-3-thia-1-aza-benzo[e]azulen-2-ylamino)-methyl]-piperidin-1-yl}-2-(2-methoxy-ethylamino)-ethanone::CHEMBL309967

SMILES: COCCNCC(=O)N1CCC(CNc2nc-3c(CCCc4ccc(F)cc-34)s2)CC1

InChI Key: InChIKey=WSBZBGJPWNFKNR-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50145277   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuropeptide Y receptor type 5 (Homo sapiens (Human))	BDBM50145277 (1-{4-[(9-Fluoro-5,6-dihydro-4H-3-thia-1-aza-benzo[...) Show SMILES COCCNCC(=O)N1CCC(CNc2nc-3c(CCCc4ccc(F)cc-34)s2)CC1 Show InChI InChI=1S/C23H31FN4O2S/c1-30-12-9-25-15-21(29)28-10-7-16(8-11-28)14-26-23-27-22-19-13-18(24)6-5-17(19)3-2-4-20(22)31-23/h5-6,13,16,25H,2-4,7-12,14-15H2,1H3,(H,26,27)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Pharma AG Curated by ChEMBL					Assay Description In vitro binding affinity of the compound against human neuropeptide Y5 receptor				Bioorg Med Chem Lett 14: 2451-7 (2004) Article DOI: 10.1016/j.bmcl.2004.03.014 BindingDB Entry DOI: 10.7270/Q2WM1CV1
					More data for this Ligand-Target Pair