BDBM50145504 (E)-3-Furan-3-yl-1-pyridin-3-yl-propenone::CHEMBL315421

SMILES: O=C(\C=C\c1ccoc1)c1cccnc1

InChI Key: InChIKey=DYOQGKXTOLQYGE-ONEGZZNKSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50145504   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin G/H synthase (cyclooxygenase) (Mus musculus)	BDBM50145504 ((E)-3-Furan-3-yl-1-pyridin-3-yl-propenone | CHEMBL...) Show SMILES O=C(\C=C\c1ccoc1)c1cccnc1 Show InChI InChI=1S/C12H9NO2/c14-12(11-2-1-6-13-8-11)4-3-10-5-7-15-9-10/h1-9H/b4-3+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
Yeungnam University Curated by ChEMBL					Assay Description Inhibitory activity against murine prostaglandin G/H synthase 1.				Bioorg Med Chem Lett 14: 2559-62 (2004) Article DOI: 10.1016/j.bmcl.2004.02.099 BindingDB Entry DOI: 10.7270/Q2VD7005
					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase (Mus musculus)	BDBM50145504 ((E)-3-Furan-3-yl-1-pyridin-3-yl-propenone | CHEMBL...) Show SMILES O=C(\C=C\c1ccoc1)c1cccnc1 Show InChI InChI=1S/C12H9NO2/c14-12(11-2-1-6-13-8-11)4-3-10-5-7-15-9-10/h1-9H/b4-3+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.34E+4	n/a	n/a	n/a	n/a	n/a	n/a
Yeungnam University Curated by ChEMBL					Assay Description Inhibitory activity against murine lipoxygenase-2.				Bioorg Med Chem Lett 14: 2559-62 (2004) Article DOI: 10.1016/j.bmcl.2004.02.099 BindingDB Entry DOI: 10.7270/Q2VD7005
					More data for this Ligand-Target Pair
Cyclooxygenase-2 (COX-2) (Mus musculus (Mouse))	BDBM50145504 ((E)-3-Furan-3-yl-1-pyridin-3-yl-propenone | CHEMBL...) Show SMILES O=C(\C=C\c1ccoc1)c1cccnc1 Show InChI InChI=1S/C12H9NO2/c14-12(11-2-1-6-13-8-11)4-3-10-5-7-15-9-10/h1-9H/b4-3+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.92E+3	n/a	n/a	n/a	n/a	n/a	n/a
Yeungnam University Curated by ChEMBL					Assay Description Inhibitory activity against murine Prostaglandin G/H synthase 2.				Bioorg Med Chem Lett 14: 2559-62 (2004) Article DOI: 10.1016/j.bmcl.2004.02.099 BindingDB Entry DOI: 10.7270/Q2VD7005
					More data for this Ligand-Target Pair