BDBM50145616 CHEMBL3763331

SMILES: Cl.Fc1ccc(cc1)C(N1CCN(CCCNC(=O)c2ccncc2)CC1)c1ccc(F)cc1

InChI Key: InChIKey=NWVQWEATHIBBPB-UHFFFAOYSA-N

Data: 5 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50145616   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(1A) dopamine receptor (RAT)	BDBM50145616 (CHEMBL3763331) Show SMILES Cl.Fc1ccc(cc1)C(N1CCN(CCCNC(=O)c2ccncc2)CC1)c1ccc(F)cc1 Show InChI InChI=1S/C26H28F2N4O.ClH/c27-23-6-2-20(3-7-23)25(21-4-8-24(28)9-5-21)32-18-16-31(17-19-32)15-1-12-30-26(33)22-10-13-29-14-11-22;/h2-11,13-14,25H,1,12,15-19H2,(H,30,33);1H	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.0983	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Dipartimento di Farmacia Universit£ di Napoli"Federico II" Curated by ChEMBL					Assay Description Displacement of [3H]SCH-23390 from dopamine D1 receptor in rat striatum incubated for 15 mins by liquid scintillation counting analysis				Eur J Med Chem 110: 133-50 (2016) BindingDB Entry DOI: 10.7270/Q24X59N9
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50145616 (CHEMBL3763331) Show SMILES Cl.Fc1ccc(cc1)C(N1CCN(CCCNC(=O)c2ccncc2)CC1)c1ccc(F)cc1 Show InChI InChI=1S/C26H28F2N4O.ClH/c27-23-6-2-20(3-7-23)25(21-4-8-24(28)9-5-21)32-18-16-31(17-19-32)15-1-12-30-26(33)22-10-13-29-14-11-22;/h2-11,13-14,25H,1,12,15-19H2,(H,30,33);1H	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.130	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Dipartimento di Farmacia Universit£ di Napoli"Federico II" Curated by ChEMBL					Assay Description Displacement of [3H]8-OH-DPAT from 5HT1A receptor in Sprague-Dawley rat brain cortex incubated for 30 mins by liquid scintillation counting analysis				Eur J Med Chem 110: 133-50 (2016) BindingDB Entry DOI: 10.7270/Q24X59N9
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50145616 (CHEMBL3763331) Show SMILES Cl.Fc1ccc(cc1)C(N1CCN(CCCNC(=O)c2ccncc2)CC1)c1ccc(F)cc1 Show InChI InChI=1S/C26H28F2N4O.ClH/c27-23-6-2-20(3-7-23)25(21-4-8-24(28)9-5-21)32-18-16-31(17-19-32)15-1-12-30-26(33)22-10-13-29-14-11-22;/h2-11,13-14,25H,1,12,15-19H2,(H,30,33);1H	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	27	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Dipartimento di Farmacia Universit£ di Napoli"Federico II" Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from dopamine D2 receptor in rat striatum incubated for 15 mins by liquid scintillation counting analysis				Eur J Med Chem 110: 133-50 (2016) BindingDB Entry DOI: 10.7270/Q24X59N9
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50145616 (CHEMBL3763331) Show SMILES Cl.Fc1ccc(cc1)C(N1CCN(CCCNC(=O)c2ccncc2)CC1)c1ccc(F)cc1 Show InChI InChI=1S/C26H28F2N4O.ClH/c27-23-6-2-20(3-7-23)25(21-4-8-24(28)9-5-21)32-18-16-31(17-19-32)15-1-12-30-26(33)22-10-13-29-14-11-22;/h2-11,13-14,25H,1,12,15-19H2,(H,30,33);1H	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Dipartimento di Farmacia Universit£ di Napoli"Federico II" Curated by ChEMBL					Assay Description Displacement of [3H]ketanserin from 5HT2A receptor in Sprague-Dawley rat brain cortex incubated for 15 mins by liquid scintillation counting analysis				Eur J Med Chem 110: 133-50 (2016) BindingDB Entry DOI: 10.7270/Q24X59N9
					More data for this Ligand-Target Pair
Serotonin (5-HT) receptor (Rattus norvegicus (Rat))	BDBM50145616 (CHEMBL3763331) Show SMILES Cl.Fc1ccc(cc1)C(N1CCN(CCCNC(=O)c2ccncc2)CC1)c1ccc(F)cc1 Show InChI InChI=1S/C26H28F2N4O.ClH/c27-23-6-2-20(3-7-23)25(21-4-8-24(28)9-5-21)32-18-16-31(17-19-32)15-1-12-30-26(33)22-10-13-29-14-11-22;/h2-11,13-14,25H,1,12,15-19H2,(H,30,33);1H	KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Dipartimento di Farmacia Universit£ di Napoli"Federico II" Curated by ChEMBL					Assay Description Displacement of [3H]mesulergine from 5HT2C receptor in Sprague-Dawley rat brain cortex incubated for 15 mins by liquid scintillation counting analysi...				Eur J Med Chem 110: 133-50 (2016) BindingDB Entry DOI: 10.7270/Q24X59N9
					More data for this Ligand-Target Pair