BDBM50145676 CHEMBL3764310

SMILES: Oc1c(Br)cc(\C=N\Nc2nc(cs2)-c2ccc(cc2)[N+]([O-])=O)cc1Br

InChI Key: InChIKey=GOSJTPMWDACDSL-FBCYGCLPSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50145676   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Leucyl-tRNA synthetase (Homo sapiens (Human))	BDBM50145676 (CHEMBL3764310) Show SMILES Oc1c(Br)cc(\C=N\Nc2nc(cs2)-c2ccc(cc2)[N+]([O-])=O)cc1Br Show InChI InChI=1S/C16H10Br2N4O3S/c17-12-5-9(6-13(18)15(12)23)7-19-21-16-20-14(8-26-16)10-1-3-11(4-2-10)22(24)25/h1-8,23H,(H,20,21)/b19-7+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.87E+4	n/a	n/a	n/a	n/a	n/a	n/a
NAS of Ukraine Curated by ChEMBL					Assay Description Inhibition of human leucyl-tRNA synthetase assessed as reduction of [14C]-L-leucine ligation to tRNA incubated for 5 mins by scintillation counting m...				Bioorg Med Chem 24: 1023-31 (2016) BindingDB Entry DOI: 10.7270/Q2RN39Q8
					More data for this Ligand-Target Pair