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SMILES: CN(C(C(=O)CCc1ccncc1)c1ccccc1Br)c1ccccc1Cl

InChI Key: InChIKey=TYZISUJFWJYTRN-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50145724   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Corticotropin-releasing factor receptor 1


(Homo sapiens (Human))		BDBM50145724
PNG
(1-(2-Bromo-phenyl)-1-[(2-chloro-phenyl)-methyl-ami...)
Show SMILES CN(C(C(=O)CCc1ccncc1)c1ccccc1Br)c1ccccc1Cl
Show InChI InChI=1S/C22H20BrClN2O/c1-26(20-9-5-4-8-19(20)24)22(17-6-2-3-7-18(17)23)21(27)11-10-16-12-14-25-15-13-16/h2-9,12-15,22H,10-11H2,1H3
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Article
PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



Bristol-Myers Squibb Pharma Research Laboratories

Curated by ChEMBL


Assay Description
Binding affinity towards human corticotropin releasing factor (h-CRF1) receptor

J Med Chem 47: 2426-9 (2004)


Article DOI: 10.1021/jm049974i
BindingDB Entry DOI: 10.7270/Q2PZ5888
More data for this
Ligand-Target Pair