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SMILES: Cc1ccccc1C(Nc1ccc(Cl)cc1Cl)C(=O)c1cccc(O)c1

InChI Key: InChIKey=YWEGKDZLNZDAPT-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50145727   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Corticotropin-releasing factor receptor 1


(Homo sapiens (Human))		BDBM50145727
PNG
(2-(2,4-Dichloro-phenylamino)-1-(3-hydroxy-phenyl)-...)
Show SMILES Cc1ccccc1C(Nc1ccc(Cl)cc1Cl)C(=O)c1cccc(O)c1
Show InChI InChI=1S/C21H17Cl2NO2/c1-13-5-2-3-8-17(13)20(21(26)14-6-4-7-16(25)11-14)24-19-10-9-15(22)12-18(19)23/h2-12,20,24-25H,1H3
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Article
PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



Bristol-Myers Squibb Pharma Research Laboratories

Curated by ChEMBL


Assay Description
Binding affinity towards human corticotropin releasing factor (h-CRF1) receptor

J Med Chem 47: 2426-9 (2004)


Article DOI: 10.1021/jm049974i
BindingDB Entry DOI: 10.7270/Q2PZ5888
More data for this
Ligand-Target Pair