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SMILES: COc1ccc(cc1O)C(=O)C(Nc1ccc(C)cc1Cl)c1ccccc1Br

InChI Key: InChIKey=LKIMBIKDLMYJGK-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50145737   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Corticotropin-releasing factor receptor 1


(Homo sapiens (Human))		BDBM50145737
PNG
(2-(2-Bromo-phenyl)-2-(2-chloro-4-methyl-phenylamin...)
Show SMILES COc1ccc(cc1O)C(=O)C(Nc1ccc(C)cc1Cl)c1ccccc1Br
Show InChI InChI=1S/C22H19BrClNO3/c1-13-7-9-18(17(24)11-13)25-21(15-5-3-4-6-16(15)23)22(27)14-8-10-20(28-2)19(26)12-14/h3-12,21,25-26H,1-2H3
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Article
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 1.07E+3n/an/an/an/an/an/an/an/a



Bristol-Myers Squibb Pharma Research Laboratories

Curated by ChEMBL


Assay Description
Binding affinity towards human corticotropin releasing factor (h-CRF1) receptor

J Med Chem 47: 2426-9 (2004)


Article DOI: 10.1021/jm049974i
BindingDB Entry DOI: 10.7270/Q2PZ5888
More data for this
Ligand-Target Pair