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SMILES: CC(=O)Nc1cccc(c1)C(=O)C(Nc1ccc(Cl)cc1Cl)c1ccccc1Br

InChI Key: InChIKey=YHUDUYJPGRCQQJ-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50145739   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Corticotropin-releasing factor receptor 1


(Homo sapiens (Human))		BDBM50145739
PNG
(CHEMBL81912 | N-{3-[2-(2-Bromo-phenyl)-2-(2,4-dich...)
Show SMILES CC(=O)Nc1cccc(c1)C(=O)C(Nc1ccc(Cl)cc1Cl)c1ccccc1Br
Show InChI InChI=1S/C22H17BrCl2N2O2/c1-13(28)26-16-6-4-5-14(11-16)22(29)21(17-7-2-3-8-18(17)23)27-20-10-9-15(24)12-19(20)25/h2-12,21,27H,1H3,(H,26,28)
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 514n/an/an/an/an/an/an/an/a



Bristol-Myers Squibb Pharma Research Laboratories

Curated by ChEMBL


Assay Description
Binding affinity towards human corticotropin releasing factor (h-CRF1) receptor

J Med Chem 47: 2426-9 (2004)


Article DOI: 10.1021/jm049974i
BindingDB Entry DOI: 10.7270/Q2PZ5888
More data for this
Ligand-Target Pair