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BDBM50145750 1-(2-Bromo-phenyl)-1-(2-chloro-4-methyl-phenylamino)-3-pyridin-4-yl-propan-2-one::CHEMBL309989

SMILES: Cc1ccc(NC(C(=O)Cc2ccncc2)c2ccccc2Br)c(Cl)c1

InChI Key: InChIKey=GLVPGJZRNLXKMM-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50145750   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Corticotropin-releasing factor receptor 1


(Homo sapiens (Human))
BDBM50145750
PNG
(1-(2-Bromo-phenyl)-1-(2-chloro-4-methyl-phenylamin...)
Show SMILES Cc1ccc(NC(C(=O)Cc2ccncc2)c2ccccc2Br)c(Cl)c1
Show InChI InChI=1S/C21H18BrClN2O/c1-14-6-7-19(18(23)12-14)25-21(16-4-2-3-5-17(16)22)20(26)13-15-8-10-24-11-9-15/h2-12,21,25H,13H2,1H3
PDB
MMDB

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PC cid
PC sid
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Similars

Article
PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



Bristol-Myers Squibb Pharma Research Laboratories

Curated by ChEMBL


Assay Description
Binding affinity towards human corticotropin releasing factor (h-CRF1) receptor


J Med Chem 47: 2426-9 (2004)


Article DOI: 10.1021/jm049974i
BindingDB Entry DOI: 10.7270/Q2PZ5888
More data for this
Ligand-Target Pair