BDBM50145857 CHEMBL3764317

SMILES: Oc1ccc2c(c(Oc3ccc(Cl)cc3)sc2c1)-c1ccc(F)cc1

InChI Key: InChIKey=UMEQMTBKQWXBIM-UHFFFAOYSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50145857   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Estrogen receptor (Homo sapiens (Human))	BDBM50145857 (CHEMBL3764317) Show SMILES Oc1ccc2c(c(Oc3ccc(Cl)cc3)sc2c1)-c1ccc(F)cc1 Show InChI InChI=1S/C20H12ClFO2S/c21-13-3-8-16(9-4-13)24-20-19(12-1-5-14(22)6-2-12)17-10-7-15(23)11-18(17)25-20/h1-11,23H	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	76	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Partial agonist activity at ERalpha in human MCF7:WS8 cells after 18 hrs by luciferase reporter gene assay				J Med Chem 59: 219-37 (2016) BindingDB Entry DOI: 10.7270/Q2N018DK
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM50145857 (CHEMBL3764317) Show SMILES Oc1ccc2c(c(Oc3ccc(Cl)cc3)sc2c1)-c1ccc(F)cc1 Show InChI InChI=1S/C20H12ClFO2S/c21-13-3-8-16(9-4-13)24-20-19(12-1-5-14(22)6-2-12)17-10-7-15(23)11-18(17)25-20/h1-11,23H	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	76	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Agonist activity at estrogen receptor alpha in human MCF7:WS8 cells after 18 hrs by dual luciferase reporter assay				J Med Chem 59: 219-37 (2016) BindingDB Entry DOI: 10.7270/Q2N018DK
					More data for this Ligand-Target Pair