BDBM50145886 CHEMBL3763349

SMILES: COCC(C)Oc1ccc(cc1Cl)C(CC1CCCC1)c1cc2cccnc2[nH]1

InChI Key: InChIKey=ZWOHLWADEZHKEZ-UHFFFAOYSA-N

Data: 1 EC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50145886   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucokinase/Glucokinase regulatory protein (Homo sapiens (Human))	BDBM50145886 (CHEMBL3763349) Show SMILES COCC(C)Oc1ccc(cc1Cl)C(CC1CCCC1)c1cc2cccnc2[nH]1 Show InChI InChI=1S/C24H29ClN2O2/c1-16(15-28-2)29-23-10-9-18(13-21(23)25)20(12-17-6-3-4-7-17)22-14-19-8-5-11-26-24(19)27-22/h5,8-11,13-14,16-17,20H,3-4,6-7,12,15H2,1-2H3,(H,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	608	n/a	n/a	n/a	n/a
Servier Research Institute of Medicinal Chemistry Curated by ChEMBL					Assay Description Activation of recombinant human glucokinase assessed as NADPH formation using glucose as substrate incubated for 30 mins in presence of NADP+ and glu...				J Med Chem 59: 687-706 (2016) BindingDB Entry DOI: 10.7270/Q2CF9S0F
					More data for this Ligand-Target Pair