BDBM50145971 2-Amino-4-[4-(2-ethyl-5,7-dimethyl-imidazo[4,5-b]pyridin-3-ylmethyl)-phenyl]-quinoline-3-carboxylic acid::CHEMBL85405

SMILES: CCc1nc2c(C)cc(C)nc2n1Cc1ccc(cc1)-c1c(C(O)=O)c(N)nc2ccccc12

InChI Key: InChIKey=ZZLVFYACIJHFAR-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50145971   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Angiotensin II AT1B (RAT)	BDBM50145971 (2-Amino-4-[4-(2-ethyl-5,7-dimethyl-imidazo[4,5-b]p...) Show SMILES CCc1nc2c(C)cc(C)nc2n1Cc1ccc(cc1)-c1c(C(O)=O)c(N)nc2ccccc12 Show InChI InChI=1S/C27H25N5O2/c1-4-21-31-24-15(2)13-16(3)29-26(24)32(21)14-17-9-11-18(12-10-17)22-19-7-5-6-8-20(19)30-25(28)23(22)27(33)34/h5-13H,4,14H2,1-3H3,(H2,28,30)(H,33,34)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Università di Siena Curated by ChEMBL					Assay Description Binding affinity for rat angiotensin II receptor, type 1				J Med Chem 47: 2574-86 (2004) Article DOI: 10.1021/jm031100t BindingDB Entry DOI: 10.7270/Q25X28DX
					More data for this Ligand-Target Pair