BDBM50146041 CHEMBL316341::[3-(3,4-Dichloro-phenyl)-6-methoxy-indan-1-yl]-diethyl-amine

SMILES: CCN(CC)C1CC(c2ccc(OC)cc12)c1ccc(Cl)c(Cl)c1

InChI Key: InChIKey=FIJOQRLYVALYIU-UHFFFAOYSA-N

Data: 6 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50146041   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium-dependent serotonin transporter (Rattus norvegicus (rat))	BDBM50146041 (CHEMBL316341 | [3-(3,4-Dichloro-phenyl)-6-methoxy-...) Show SMILES CCN(CC)C1CC(c2ccc(OC)cc12)c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C20H23Cl2NO/c1-4-23(5-2)20-12-16(13-6-9-18(21)19(22)10-13)15-8-7-14(24-3)11-17(15)20/h6-11,16,20H,4-5,12H2,1-3H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Displacement of [125I]RTI-55 from serotonin transporter of frozen rat caudate membranes				J Med Chem 47: 2624-34 (2004) Article DOI: 10.1021/jm0305873 BindingDB Entry DOI: 10.7270/Q2MK6DF4
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Rattus norvegicus (rat))	BDBM50146041 (CHEMBL316341 | [3-(3,4-Dichloro-phenyl)-6-methoxy-...) Show SMILES CCN(CC)C1CC(c2ccc(OC)cc12)c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C20H23Cl2NO/c1-4-23(5-2)20-12-16(13-6-9-18(21)19(22)10-13)15-8-7-14(24-3)11-17(15)20/h6-11,16,20H,4-5,12H2,1-3H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	26	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Displacement of [125I]RTI-55 from serotonin transporter of frozen rat caudate membranes				J Med Chem 47: 2624-34 (2004) Article DOI: 10.1021/jm0305873 BindingDB Entry DOI: 10.7270/Q2MK6DF4
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50146041 (CHEMBL316341 | [3-(3,4-Dichloro-phenyl)-6-methoxy-...) Show SMILES CCN(CC)C1CC(c2ccc(OC)cc12)c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C20H23Cl2NO/c1-4-23(5-2)20-12-16(13-6-9-18(21)19(22)10-13)15-8-7-14(24-3)11-17(15)20/h6-11,16,20H,4-5,12H2,1-3H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	140	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Reuptake inhibitory activity against dopamine DA transporter				J Med Chem 47: 2624-34 (2004) Article DOI: 10.1021/jm0305873 BindingDB Entry DOI: 10.7270/Q2MK6DF4
					More data for this Ligand-Target Pair
Norepinephrine Monoamine transporters (Rattus norvegicus)	BDBM50146041 (CHEMBL316341 | [3-(3,4-Dichloro-phenyl)-6-methoxy-...) Show SMILES CCN(CC)C1CC(c2ccc(OC)cc12)c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C20H23Cl2NO/c1-4-23(5-2)20-12-16(13-6-9-18(21)19(22)10-13)15-8-7-14(24-3)11-17(15)20/h6-11,16,20H,4-5,12H2,1-3H3	Reactome pathway KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.01E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Displacement of from norepinephrine transporter of frozen rat caudate membranes				J Med Chem 47: 2624-34 (2004) Article DOI: 10.1021/jm0305873 BindingDB Entry DOI: 10.7270/Q2MK6DF4
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50146041 (CHEMBL316341 | [3-(3,4-Dichloro-phenyl)-6-methoxy-...) Show SMILES CCN(CC)C1CC(c2ccc(OC)cc12)c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C20H23Cl2NO/c1-4-23(5-2)20-12-16(13-6-9-18(21)19(22)10-13)15-8-7-14(24-3)11-17(15)20/h6-11,16,20H,4-5,12H2,1-3H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.31E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Binding affinity for DA transporter using [125I]RTI-55 in frozen rat caudate membranes				J Med Chem 47: 2624-34 (2004) Article DOI: 10.1021/jm0305873 BindingDB Entry DOI: 10.7270/Q2MK6DF4
					More data for this Ligand-Target Pair
Monoamine transporters; Norepininephrine & dopamine (Rattus norvegicus)	BDBM50146041 (CHEMBL316341 | [3-(3,4-Dichloro-phenyl)-6-methoxy-...) Show SMILES CCN(CC)C1CC(c2ccc(OC)cc12)c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C20H23Cl2NO/c1-4-23(5-2)20-12-16(13-6-9-18(21)19(22)10-13)15-8-7-14(24-3)11-17(15)20/h6-11,16,20H,4-5,12H2,1-3H3	Reactome pathway KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>4.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Displacement of from norepinephrine transporter of frozen rat caudate membranes				J Med Chem 47: 2624-34 (2004) Article DOI: 10.1021/jm0305873 BindingDB Entry DOI: 10.7270/Q2MK6DF4
					More data for this Ligand-Target Pair