BDBM50146416 (S)-2-[(S)-2-[(S)-2-(5-Hydroxy-4-oxo-4H-pyran-2-ylmethoxycarbonylamino)-1-oxo-3-phenyl-propylamino]-3-(1H-indol-3-yl)-propionylamino]-3-(4-hydroxy-phenyl)-propionic acid::CHEMBL317040

SMILES: OC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1ccccc1)NC(=O)OCc1cc(=O)c(O)co1

InChI Key: InChIKey=AOMOJQKAHRHJLR-DTXPUJKBSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50146416   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosinase (Homo sapiens (Human))	BDBM50146416 ((S)-2-[(S)-2-[(S)-2-(5-Hydroxy-4-oxo-4H-pyran-2-yl...) Show SMILES OC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1ccccc1)NC(=O)OCc1cc(=O)c(O)co1 Show InChI InChI=1S/C36H34N4O10/c41-24-12-10-22(11-13-24)15-30(35(46)47)39-34(45)29(16-23-18-37-27-9-5-4-8-26(23)27)38-33(44)28(14-21-6-2-1-3-7-21)40-36(48)50-19-25-17-31(42)32(43)20-49-25/h1-13,17-18,20,28-30,37,41,43H,14-16,19H2,(H,38,44)(H,39,45)(H,40,48)(H,46,47)/t28-,29-,30-/m0/s1	KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	240	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Inhibitory activity against mushroom tyrosinase				Bioorg Med Chem Lett 14: 2843-6 (2004) Article DOI: 10.1016/j.bmcl.2004.03.046 BindingDB Entry DOI: 10.7270/Q2N015ZH
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