BDBM50146444 8-Ethylsulfanyl-5-pyridin-2-yl-3,4-dihydro-2H-naphthalen-1-one::CHEMBL95268

SMILES: CCSc1ccc(c2CCCC(=O)c12)-c1ccccn1

InChI Key: InChIKey=GIWBACLLMIJHCB-UHFFFAOYSA-N

Data: 4 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50146444   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
GABA receptor alpha-5/beta-3/gamma-2 subunit (Homo sapiens (Human))	BDBM50146444 (8-Ethylsulfanyl-5-pyridin-2-yl-3,4-dihydro-2H-naph...) Show SMILES CCSc1ccc(c2CCCC(=O)c12)-c1ccccn1 Show InChI InChI=1S/C17H17NOS/c1-2-20-16-10-9-12(14-7-3-4-11-18-14)13-6-5-8-15(19)17(13)16/h3-4,7,9-11H,2,5-6,8H2,1H3	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	103	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Curated by ChEMBL					Assay Description Inhibition of [3H]-Ro- 15-1788 binding to human GABA-A receptor alpha-5-beta-3-gamma-2 subunits				Bioorg Med Chem Lett 14: 2871-5 (2004) Article DOI: 10.1016/j.bmcl.2004.03.054 BindingDB Entry DOI: 10.7270/Q2KW5GK5
					More data for this Ligand-Target Pair
GABA receptor alpha-1/beta-3/gamma-2 subunit (Homo sapiens (Human))	BDBM50146444 (8-Ethylsulfanyl-5-pyridin-2-yl-3,4-dihydro-2H-naph...) Show SMILES CCSc1ccc(c2CCCC(=O)c12)-c1ccccn1 Show InChI InChI=1S/C17H17NOS/c1-2-20-16-10-9-12(14-7-3-4-11-18-14)13-6-5-8-15(19)17(13)16/h3-4,7,9-11H,2,5-6,8H2,1H3	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	>300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Curated by ChEMBL					Assay Description Inhibition of [3H]-Ro- 15-1788 binding to recombinant human gamma-aminobutyric-acid A receptor alpha-1-beta-3-gamma-2				Bioorg Med Chem Lett 14: 2871-5 (2004) Article DOI: 10.1016/j.bmcl.2004.03.054 BindingDB Entry DOI: 10.7270/Q2KW5GK5
					More data for this Ligand-Target Pair
GABA receptor alpha-2/beta-3/gamma-2 subunit (Homo sapiens (Human))	BDBM50146444 (8-Ethylsulfanyl-5-pyridin-2-yl-3,4-dihydro-2H-naph...) Show SMILES CCSc1ccc(c2CCCC(=O)c12)-c1ccccn1 Show InChI InChI=1S/C17H17NOS/c1-2-20-16-10-9-12(14-7-3-4-11-18-14)13-6-5-8-15(19)17(13)16/h3-4,7,9-11H,2,5-6,8H2,1H3	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	>300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Curated by ChEMBL					Assay Description Inhibition of [3H]-Ro- 15-1788 binding to recombinant human gamma-aminobutyric-acid A receptor alpha-2-beta-3-gamma-2				Bioorg Med Chem Lett 14: 2871-5 (2004) Article DOI: 10.1016/j.bmcl.2004.03.054 BindingDB Entry DOI: 10.7270/Q2KW5GK5
					More data for this Ligand-Target Pair
GABA receptor alpha-3/beta-3/gamma-2 subunit (Homo sapiens (Human))	BDBM50146444 (8-Ethylsulfanyl-5-pyridin-2-yl-3,4-dihydro-2H-naph...) Show SMILES CCSc1ccc(c2CCCC(=O)c12)-c1ccccn1 Show InChI InChI=1S/C17H17NOS/c1-2-20-16-10-9-12(14-7-3-4-11-18-14)13-6-5-8-15(19)17(13)16/h3-4,7,9-11H,2,5-6,8H2,1H3	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	>300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Curated by ChEMBL					Assay Description Inhibition of [3H]-Ro- 15-1788 binding to recombinant human gamma-aminobutyric-acid A receptor alpha-3-beta-3-gamma-2				Bioorg Med Chem Lett 14: 2871-5 (2004) Article DOI: 10.1016/j.bmcl.2004.03.054 BindingDB Entry DOI: 10.7270/Q2KW5GK5
					More data for this Ligand-Target Pair