BDBM50146482 3-({1-[3-(4,5-Dihydro-1H-imidazol-2-ylamino)-phenyl]-5-oxo-pyrrolidine-3-carbonyl}-amino)-3-pyridin-3-yl-propionic acid::CHEMBL100151

SMILES: OC(=O)CC(NC(=O)C1CN(C(=O)C1)c1cccc(NC2=NCCN2)c1)c1cccnc1

InChI Key: InChIKey=OSFFDUZCJDKYFG-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50146482   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
ITGAV/ITGB3 (Homo sapiens (Human))	BDBM50146482 (3-({1-[3-(4,5-Dihydro-1H-imidazol-2-ylamino)-pheny...) Show SMILES OC(=O)CC(NC(=O)C1CN(C(=O)C1)c1cccc(NC2=NCCN2)c1)c1cccnc1 |t:21| Show InChI InChI=1S/C22H24N6O4/c29-19-9-15(21(32)27-18(11-20(30)31)14-3-2-6-23-12-14)13-28(19)17-5-1-4-16(10-17)26-22-24-7-8-25-22/h1-6,10,12,15,18H,7-9,11,13H2,(H,27,32)(H,30,31)(H2,24,25,26)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	5.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Affinity for alphaIIb-beta3 integrin				Bioorg Med Chem Lett 14: 2905-9 (2004) Article DOI: 10.1016/j.bmcl.2004.03.033 BindingDB Entry DOI: 10.7270/Q2416WJD
					More data for this Ligand-Target Pair