BDBM50146609 (Z)-3-Benzyl-2-(7-methoxy-benzo[1,3]dioxol-5-yl)-4-(4-methoxy-phenyl)-4-oxo-but-2-enoic acid::CHEMBL369085

SMILES: COc1ccc(cc1)C(=O)C(\Cc1ccccc1)=C(/C(O)=O)c1cc2OCOc2c(OC)c1

InChI Key: InChIKey=HKLZPDIAPVJSFU-ATJXCDBQSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50146609   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
EDNRA (RAT)	BDBM50146609 ((Z)-3-Benzyl-2-(7-methoxy-benzo[1,3]dioxol-5-yl)-4...) Show SMILES COc1ccc(cc1)C(=O)C(\Cc1ccccc1)=C(/C(O)=O)c1cc2OCOc2c(OC)c1 Show InChI InChI=1S/C26H22O7/c1-30-19-10-8-17(9-11-19)24(27)20(12-16-6-4-3-5-7-16)23(26(28)29)18-13-21(31-2)25-22(14-18)32-15-33-25/h3-11,13-14H,12,15H2,1-2H3,(H,28,29)/b23-20-	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.70	n/a	n/a	n/a	n/a	n/a	n/a
University of Innsbruck Curated by ChEMBL					Assay Description Ability to displace [125I]-ET-1 from the rat endothelin A receptor expressed in rat aorta smooth muscle cells.				J Med Chem 47: 2750-60 (2004) Article DOI: 10.1021/jm031041j BindingDB Entry DOI: 10.7270/Q26T0M3J
					More data for this Ligand-Target Pair