BDBM50146633 1-[4-(4-Imidazol-1-yl-phenoxy)-piperidine-1-sulfonyl]-piperidine-2-carboxylic acid hydroxyamide::CHEMBL316320

SMILES: ONC(=O)C1CCCCN1S(=O)(=O)N1CCC(CC1)Oc1ccc(cc1)-n1ccnc1

InChI Key: InChIKey=HFLIURRFGRQVSH-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50146633   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Interstitial collagenase (Homo sapiens (Human))	BDBM50146633 (1-[4-(4-Imidazol-1-yl-phenoxy)-piperidine-1-sulfon...) Show SMILES ONC(=O)C1CCCCN1S(=O)(=O)N1CCC(CC1)Oc1ccc(cc1)-n1ccnc1 Show InChI InChI=1S/C20H27N5O5S/c26-20(22-27)19-3-1-2-11-25(19)31(28,29)24-12-8-18(9-13-24)30-17-6-4-16(5-7-17)23-14-10-21-15-23/h4-7,10,14-15,18-19,27H,1-3,8-9,11-13H2,(H,22,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	224	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
De Novo Pharmaceuticals Ltd. Curated by ChEMBL					Assay Description Inhibition of human matrix metalloprotease-1				J Med Chem 47: 2761-7 (2004) Article DOI: 10.1021/jm031061l BindingDB Entry DOI: 10.7270/Q2ZG6T0B
					More data for this Ligand-Target Pair