BDBM50146769 2-[4-(3-Chloro-6-oxo-5,6-dihydro-4H-pyridazin-1-yl)-butyl]-4-methyl-6-propyl-1,4-dihydro-imidazo[4,5-b]pyridine-5,7-dione::CHEMBL94548

SMILES: CCCc1c(O)c2[nH]c(CCCCN3N=C(Cl)CCC3=O)nc2n(C)c1=O

InChI Key: InChIKey=SWRAISUSKJJFEA-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50146769   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Adenosine receptor A1 (Homo sapiens (Human))	BDBM50146769 (2-[4-(3-Chloro-6-oxo-5,6-dihydro-4H-pyridazin-1-yl...) Show SMILES CCCc1c(O)c2[nH]c(CCCCN3N=C(Cl)CCC3=O)nc2n(C)c1=O |t:14| Show InChI InChI=1S/C18H24ClN5O3/c1-3-6-11-16(26)15-17(23(2)18(11)27)21-13(20-15)7-4-5-10-24-14(25)9-8-12(19)22-24/h26H,3-10H2,1-2H3,(H,20,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	190	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universitat Pompeu Fabra Curated by ChEMBL					Assay Description Binding affinity at adenosine A1 receptor.				J Med Chem 47: 2805-15 (2004) Article DOI: 10.1021/jm0311240 BindingDB Entry DOI: 10.7270/Q22J6CMN
					More data for this Ligand-Target Pair