BDBM50147243 4-Isopropyl-3-methyl-2-(piperidine-1-carbonyl)-2H-isoxazol-5-one::4-isopropyl-3-methyl-2-(piperidine-1-carbonyl)isoxazol-5(2H)-one::CHEMBL109116

SMILES: CC(C)c1c(C)n(oc1=O)C(=O)N1CCCCC1

InChI Key: InChIKey=FEFGIBYVJBBQHF-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50147243   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hormone-sensitive lipase (HSL) (Homo sapiens (Human))	BDBM50147243 (4-Isopropyl-3-methyl-2-(piperidine-1-carbonyl)-2H-...) Show SMILES CC(C)c1c(C)n(oc1=O)C(=O)N1CCCCC1 Show InChI InChI=1S/C13H20N2O3/c1-9(2)11-10(3)15(18-12(11)16)13(17)14-7-5-4-6-8-14/h9H,4-8H2,1-3H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	75	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Research Center Curated by ChEMBL					Assay Description Inhibition of forskolin-stimulated lipolysis in differentiated 3T3-L1 cells				Bioorg Med Chem Lett 14: 3155-9 (2004) Article DOI: 10.1016/j.bmcl.2004.04.015 BindingDB Entry DOI: 10.7270/Q2NV9HQ5
					More data for this Ligand-Target Pair
Hormone sensitive lipase (Homo sapiens (Human))	BDBM50147243 (4-Isopropyl-3-methyl-2-(piperidine-1-carbonyl)-2H-...) Show SMILES CC(C)c1c(C)n(oc1=O)C(=O)N1CCCCC1 Show InChI InChI=1S/C13H20N2O3/c1-9(2)11-10(3)15(18-12(11)16)13(17)14-7-5-4-6-8-14/h9H,4-8H2,1-3H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Research Center Curated by ChEMBL					Assay Description Inhibition of human recombinant hormone sensitive lipase (HSL)				Bioorg Med Chem Lett 14: 3155-9 (2004) Article DOI: 10.1016/j.bmcl.2004.04.015 BindingDB Entry DOI: 10.7270/Q2NV9HQ5
					More data for this Ligand-Target Pair
Hormone-sensitive lipase (HSL) (Rattus norvegicus (Rat))	BDBM50147243 (4-Isopropyl-3-methyl-2-(piperidine-1-carbonyl)-2H-...) Show SMILES CC(C)c1c(C)n(oc1=O)C(=O)N1CCCCC1 Show InChI InChI=1S/C13H20N2O3/c1-9(2)11-10(3)15(18-12(11)16)13(17)14-7-5-4-6-8-14/h9H,4-8H2,1-3H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
University of Jordan Curated by ChEMBL					Assay Description Inhibition of HSL in Wistar rat isolated fat cells by spectrophotometric assay				J Med Chem 51: 6478-94 (2008) Article DOI: 10.1021/jm800718k BindingDB Entry DOI: 10.7270/Q23778KJ
					More data for this Ligand-Target Pair