BDBM50147251 4-Isopropyl-3-methyl-5-oxo-5H-isoxazole-2-carboxylic acid methyl-thiophen-2-ylmethyl-amide::4-isopropyl-N,3-dimethyl-5-oxo-N-(thiophen-2-ylmethyl)isoxazole-2(5H)-carboxamide::CHEMBL107197

SMILES: CC(C)c1c(C)n(oc1=O)C(=O)N(C)Cc1cccs1

InChI Key: InChIKey=SDWXGFHYHUHBFP-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50147251   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hormone-sensitive lipase (HSL) (Homo sapiens (Human))	BDBM50147251 (4-Isopropyl-3-methyl-5-oxo-5H-isoxazole-2-carboxyl...) Show SMILES CC(C)c1c(C)n(oc1=O)C(=O)N(C)Cc1cccs1 Show InChI InChI=1S/C14H18N2O3S/c1-9(2)12-10(3)16(19-13(12)17)14(18)15(4)8-11-6-5-7-20-11/h5-7,9H,8H2,1-4H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Research Center Curated by ChEMBL					Assay Description Inhibition of human recombinant hormone sensitive lipase (HSL)				Bioorg Med Chem Lett 14: 3155-9 (2004) Article DOI: 10.1016/j.bmcl.2004.04.015 BindingDB Entry DOI: 10.7270/Q2NV9HQ5
					More data for this Ligand-Target Pair
Hormone sensitive lipase (Homo sapiens (Human))	BDBM50147251 (4-Isopropyl-3-methyl-5-oxo-5H-isoxazole-2-carboxyl...) Show SMILES CC(C)c1c(C)n(oc1=O)C(=O)N(C)Cc1cccs1 Show InChI InChI=1S/C14H18N2O3S/c1-9(2)12-10(3)16(19-13(12)17)14(18)15(4)8-11-6-5-7-20-11/h5-7,9H,8H2,1-4H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Research Center Curated by ChEMBL					Assay Description Inhibition of human recombinant hormone sensitive lipase (HSL)				Bioorg Med Chem Lett 14: 3155-9 (2004) Article DOI: 10.1016/j.bmcl.2004.04.015 BindingDB Entry DOI: 10.7270/Q2NV9HQ5
					More data for this Ligand-Target Pair
Hormone-sensitive lipase (HSL) (Rattus norvegicus (Rat))	BDBM50147251 (4-Isopropyl-3-methyl-5-oxo-5H-isoxazole-2-carboxyl...) Show SMILES CC(C)c1c(C)n(oc1=O)C(=O)N(C)Cc1cccs1 Show InChI InChI=1S/C14H18N2O3S/c1-9(2)12-10(3)16(19-13(12)17)14(18)15(4)8-11-6-5-7-20-11/h5-7,9H,8H2,1-4H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
University of Jordan Curated by ChEMBL					Assay Description Inhibition of HSL in Wistar rat isolated fat cells by spectrophotometric assay				J Med Chem 51: 6478-94 (2008) Article DOI: 10.1021/jm800718k BindingDB Entry DOI: 10.7270/Q23778KJ
					More data for this Ligand-Target Pair