BDBM50147260 4-Isopropyl-3-methyl-5-oxo-5H-isoxazole-2-carboxylic acid benzyl-methyl-amide::CHEMBL106314::N-benzyl-4-isopropyl-N,3-dimethyl-5-oxoisoxazole-2(5H)-carboxamide

SMILES: CC(C)c1c(C)n(oc1=O)C(=O)N(C)Cc1ccccc1

InChI Key: InChIKey=RCLSTPIEXORMJO-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50147260   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hormone-sensitive lipase (HSL) (Homo sapiens (Human))	BDBM50147260 (4-Isopropyl-3-methyl-5-oxo-5H-isoxazole-2-carboxyl...) Show SMILES CC(C)c1c(C)n(oc1=O)C(=O)N(C)Cc1ccccc1 Show InChI InChI=1S/C16H20N2O3/c1-11(2)14-12(3)18(21-15(14)19)16(20)17(4)10-13-8-6-5-7-9-13/h5-9,11H,10H2,1-4H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	67	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Research Center Curated by ChEMBL					Assay Description Inhibition of forskolin-stimulated lipolysis in differentiated 3T3-L1 cells				Bioorg Med Chem Lett 14: 3155-9 (2004) Article DOI: 10.1016/j.bmcl.2004.04.015 BindingDB Entry DOI: 10.7270/Q2NV9HQ5
					More data for this Ligand-Target Pair
Hormone sensitive lipase (Homo sapiens (Human))	BDBM50147260 (4-Isopropyl-3-methyl-5-oxo-5H-isoxazole-2-carboxyl...) Show SMILES CC(C)c1c(C)n(oc1=O)C(=O)N(C)Cc1ccccc1 Show InChI InChI=1S/C16H20N2O3/c1-11(2)14-12(3)18(21-15(14)19)16(20)17(4)10-13-8-6-5-7-9-13/h5-9,11H,10H2,1-4H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Research Center Curated by ChEMBL					Assay Description Inhibition of forskolin-stimulated lipolysis in differentiated 3T3-L1 cells				Bioorg Med Chem Lett 14: 3155-9 (2004) Article DOI: 10.1016/j.bmcl.2004.04.015 BindingDB Entry DOI: 10.7270/Q2NV9HQ5
					More data for this Ligand-Target Pair
Hormone-sensitive lipase (HSL) (Rattus norvegicus (Rat))	BDBM50147260 (4-Isopropyl-3-methyl-5-oxo-5H-isoxazole-2-carboxyl...) Show SMILES CC(C)c1c(C)n(oc1=O)C(=O)N(C)Cc1ccccc1 Show InChI InChI=1S/C16H20N2O3/c1-11(2)14-12(3)18(21-15(14)19)16(20)17(4)10-13-8-6-5-7-9-13/h5-9,11H,10H2,1-4H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
University of Jordan Curated by ChEMBL					Assay Description Inhibition of HSL in Wistar rat isolated fat cells by spectrophotometric assay				J Med Chem 51: 6478-94 (2008) Article DOI: 10.1021/jm800718k BindingDB Entry DOI: 10.7270/Q23778KJ
					More data for this Ligand-Target Pair