BDBM50147270 3-Methyl-4-(2-phenoxy-ethyl)-2-(piperidine-1-carbonyl)-2H-isoxazol-5-one::3-methyl-4-(2-phenoxyethyl)-2-(piperidine-1-carbonyl)isoxazol-5(2H)-one::CHEMBL110343

SMILES: Cc1c(CCOc2ccccc2)c(=O)on1C(=O)N1CCCCC1

InChI Key: InChIKey=PBPHFBAFGKICDM-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50147270   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hormone-sensitive lipase (HSL) (Homo sapiens (Human))	BDBM50147270 (3-Methyl-4-(2-phenoxy-ethyl)-2-(piperidine-1-carbo...) Show SMILES Cc1c(CCOc2ccccc2)c(=O)on1C(=O)N1CCCCC1 Show InChI InChI=1S/C18H22N2O4/c1-14-16(10-13-23-15-8-4-2-5-9-15)17(21)24-20(14)18(22)19-11-6-3-7-12-19/h2,4-5,8-9H,3,6-7,10-13H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Research Center Curated by ChEMBL					Assay Description Inhibition of forskolin-stimulated lipolysis in differentiated 3T3-L1 cells				Bioorg Med Chem Lett 14: 3155-9 (2004) Article DOI: 10.1016/j.bmcl.2004.04.015 BindingDB Entry DOI: 10.7270/Q2NV9HQ5
					More data for this Ligand-Target Pair
Hormone sensitive lipase (Homo sapiens (Human))	BDBM50147270 (3-Methyl-4-(2-phenoxy-ethyl)-2-(piperidine-1-carbo...) Show SMILES Cc1c(CCOc2ccccc2)c(=O)on1C(=O)N1CCCCC1 Show InChI InChI=1S/C18H22N2O4/c1-14-16(10-13-23-15-8-4-2-5-9-15)17(21)24-20(14)18(22)19-11-6-3-7-12-19/h2,4-5,8-9H,3,6-7,10-13H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Research Center Curated by ChEMBL					Assay Description Inhibition of human recombinant hormone sensitive lipase (HSL)				Bioorg Med Chem Lett 14: 3155-9 (2004) Article DOI: 10.1016/j.bmcl.2004.04.015 BindingDB Entry DOI: 10.7270/Q2NV9HQ5
					More data for this Ligand-Target Pair
Hormone-sensitive lipase (HSL) (Rattus norvegicus (Rat))	BDBM50147270 (3-Methyl-4-(2-phenoxy-ethyl)-2-(piperidine-1-carbo...) Show SMILES Cc1c(CCOc2ccccc2)c(=O)on1C(=O)N1CCCCC1 Show InChI InChI=1S/C18H22N2O4/c1-14-16(10-13-23-15-8-4-2-5-9-15)17(21)24-20(14)18(22)19-11-6-3-7-12-19/h2,4-5,8-9H,3,6-7,10-13H2,1H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
University of Jordan Curated by ChEMBL					Assay Description Inhibition of HSL in Wistar rat isolated fat cells by spectrophotometric assay				J Med Chem 51: 6478-94 (2008) Article DOI: 10.1021/jm800718k BindingDB Entry DOI: 10.7270/Q23778KJ
					More data for this Ligand-Target Pair