BDBM50147430 CHEMBL109632::N-Isoquinolin-3-yl-guanidine

SMILES: [#7]\[#6](-[#7])=[#7]\c1cc2ccccc2cn1

InChI Key: InChIKey=IYISMCVOBXXKHZ-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50147430   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Urokinase-type plasminogen activator (Homo sapiens (Human))	BDBM50147430 (CHEMBL109632 | N-Isoquinolin-3-yl-guanidine) Show SMILES [#7]\[#6](-[#7])=[#7]\c1cc2ccccc2cn1 Show InChI InChI=1S/C10H10N4/c11-10(12)14-9-5-7-3-1-2-4-8(7)6-13-9/h1-6H,(H4,11,12,13,14)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	9.30E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibitory activity against human urokinase-type plasminogen activator was evaluated using S-2444 as substrate				Bioorg Med Chem Lett 14: 3227-30 (2004) Article DOI: 10.1016/j.bmcl.2004.03.094 BindingDB Entry DOI: 10.7270/Q2125S3C
					More data for this Ligand-Target Pair