BDBM50147661 CHEMBL325350::[5-Amino-2-(5-bromo-furan-2-yl)-[1,2,4]triazolo[1,5-a]pyridin-7-yl]-pyrrolidin-1-yl-methanone

SMILES: Nc1cc(cc2nc(nn12)-c1ccc(Br)o1)C(=O)N1CCCC1

InChI Key: InChIKey=VVRYFSHYYXQKHO-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50147661   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Adenosine receptor A2a (Homo sapiens (Human))	BDBM50147661 (CHEMBL325350 | [5-Amino-2-(5-bromo-furan-2-yl)-[1,...) Show SMILES Nc1cc(cc2nc(nn12)-c1ccc(Br)o1)C(=O)N1CCCC1 Show InChI InChI=1S/C15H14BrN5O2/c16-11-4-3-10(23-11)14-18-13-8-9(7-12(17)21(13)19-14)15(22)20-5-1-2-6-20/h3-4,7-8H,1-2,5-6,17H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-LaRoche Ltd Curated by ChEMBL					Assay Description Binding affinity against human Adenosine A2a receptor (hA2a)				Bioorg Med Chem Lett 14: 3307-12 (2004) Article DOI: 10.1016/j.bmcl.2004.03.104 BindingDB Entry DOI: 10.7270/Q2VD6XWM
					More data for this Ligand-Target Pair