Found 4 hits for monomerid = 50147736 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50147736
(CHEMBL3763861)Show SMILES NS(=O)(=O)c1ccc(cc1)-n1c(S)nc2cc(Cl)ccc2c1=O Show InChI InChI=1S/C14H10ClN3O3S2/c15-8-1-6-11-12(7-8)17-14(22)18(13(11)19)9-2-4-10(5-3-9)23(16,20)21/h1-7H,(H,17,22)(H2,16,20,21) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| 5.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
DAIS
Curated by ChEMBL
| Assay Description Inhibition of human recombinant carbonic anhydrase 2 preincubated for 15 mins by stopped flow CO2 hydration assay |
Bioorg Med Chem 24: 1402-7 (2016)
BindingDB Entry DOI: 10.7270/Q27H1MG2 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 12
(Homo sapiens (Human)) | BDBM50147736
(CHEMBL3763861)Show SMILES NS(=O)(=O)c1ccc(cc1)-n1c(S)nc2cc(Cl)ccc2c1=O Show InChI InChI=1S/C14H10ClN3O3S2/c15-8-1-6-11-12(7-8)17-14(22)18(13(11)19)9-2-4-10(5-3-9)23(16,20)21/h1-7H,(H,17,22)(H2,16,20,21) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| 35 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
DAIS
Curated by ChEMBL
| Assay Description Inhibition of human recombinant carbonic anhydrase 12 preincubated for 15 mins by stopped flow CO2 hydration assay |
Bioorg Med Chem 24: 1402-7 (2016)
BindingDB Entry DOI: 10.7270/Q27H1MG2 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 9
(Homo sapiens (Human)) | BDBM50147736
(CHEMBL3763861)Show SMILES NS(=O)(=O)c1ccc(cc1)-n1c(S)nc2cc(Cl)ccc2c1=O Show InChI InChI=1S/C14H10ClN3O3S2/c15-8-1-6-11-12(7-8)17-14(22)18(13(11)19)9-2-4-10(5-3-9)23(16,20)21/h1-7H,(H,17,22)(H2,16,20,21) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| 157 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
DAIS
Curated by ChEMBL
| Assay Description Inhibition of human recombinant carbonic anhydrase 9 preincubated for 15 mins by stopped flow CO2 hydration assay |
Bioorg Med Chem 24: 1402-7 (2016)
BindingDB Entry DOI: 10.7270/Q27H1MG2 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 1
(Homo sapiens (Human)) | BDBM50147736
(CHEMBL3763861)Show SMILES NS(=O)(=O)c1ccc(cc1)-n1c(S)nc2cc(Cl)ccc2c1=O Show InChI InChI=1S/C14H10ClN3O3S2/c15-8-1-6-11-12(7-8)17-14(22)18(13(11)19)9-2-4-10(5-3-9)23(16,20)21/h1-7H,(H,17,22)(H2,16,20,21) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| 172 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
DAIS
Curated by ChEMBL
| Assay Description Inhibition of human recombinant carbonic anhydrase 1 preincubated for 15 mins by stopped flow CO2 hydration assay |
Bioorg Med Chem 24: 1402-7 (2016)
BindingDB Entry DOI: 10.7270/Q27H1MG2 |
More data for this Ligand-Target Pair | |