BDBM50147972 2-(R)-Cyclohexyl-N-(2-{4-[5-(2,3-dimethyl-phenyl)-2H-pyrazol-3-yl]-piperidin-1-yl}-2-oxo-ethyl)-2-guanidino-acetamide::CHEMBL106368

SMILES: Cc1cccc(-c2cc([nH]n2)C2CCN(CC2)C(=O)CNC(=O)[C@H](N=C(N)N)C2CCCCC2)c1C

InChI Key: InChIKey=BVUICRXIFODRFJ-RUZDIDTESA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50147972   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Interleukin-2 receptor alpha chain (Mus musculus)	BDBM50147972 (2-(R)-Cyclohexyl-N-(2-{4-[5-(2,3-dimethyl-phenyl)-...) Show SMILES Cc1cccc(-c2cc([nH]n2)C2CCN(CC2)C(=O)CNC(=O)[C@H](N=C(N)N)C2CCCCC2)c1C |wD:23.25,(-6.99,-8.1,;-6.99,-6.56,;-8.32,-5.79,;-8.32,-4.25,;-6.99,-3.48,;-5.64,-4.25,;-4.36,-3.39,;-2.91,-3.93,;-1.96,-2.71,;-2.82,-1.45,;-4.31,-1.87,;-.42,-2.78,;.29,-4.15,;1.82,-4.21,;2.64,-2.91,;1.92,-1.55,;.38,-1.48,;4.18,-2.97,;4.9,-4.34,;5,-1.68,;6.54,-1.73,;7.37,-.43,;6.65,.92,;8.91,-.5,;9.73,.81,;11.27,.74,;11.97,-.63,;12.09,2.04,;9.61,-1.87,;11.15,-1.92,;11.85,-3.3,;11.03,-4.59,;9.49,-4.52,;8.78,-3.16,;-5.64,-5.79,;-4.31,-6.56,)| Show InChI InChI=1S/C27H39N7O2/c1-17-7-6-10-21(18(17)2)23-15-22(32-33-23)19-11-13-34(14-12-19)24(35)16-30-26(36)25(31-27(28)29)20-8-4-3-5-9-20/h6-7,10,15,19-20,25H,3-5,8-9,11-14,16H2,1-2H3,(H,30,36)(H,32,33)(H4,28,29,31)/t25-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30E+5	n/a	n/a	n/a	n/a	n/a	n/a
Sunesis Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Concentration required to inhibit mouse interleukin-2 alpha receptor was determined by SPA assay				J Med Chem 47: 3111-30 (2004) Article DOI: 10.1021/jm049967u BindingDB Entry DOI: 10.7270/Q2TQ6280
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