BDBM50147977 2-Cyclohexyl-N-(2-{4-[3-(2,4-dichloro-phenyl)-[1,2,4]oxadiazol-5-yl]-piperidin-1-yl}-2-oxo-ethyl)-2-guanidino-acetamide::CHEMBL105023

SMILES: [#7]\[#6](-[#7])=[#7]/[#6@H](-[#6]-1-[#6]-[#6]-[#6]-[#6]-[#6]-1)-[#6](=O)-[#7]-[#6]-[#6](=O)-[#7]-1-[#6]-[#6]-[#6](-[#6]-[#6]-1)-c1nc(no1)-c1ccc(Cl)cc1Cl

InChI Key: InChIKey=GDKUZGFWZLGNRP-HXUWFJFHSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50147977   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Interleukin-2 receptor alpha chain (Mus musculus)	BDBM50147977 (2-Cyclohexyl-N-(2-{4-[3-(2,4-dichloro-phenyl)-[1,2...) Show SMILES [#7]\[#6](-[#7])=[#7]/[#6@H](-[#6]-1-[#6]-[#6]-[#6]-[#6]-[#6]-1)-[#6](=O)-[#7]-[#6]-[#6](=O)-[#7]-1-[#6]-[#6]-[#6](-[#6]-[#6]-1)-c1nc(no1)-c1ccc(Cl)cc1Cl Show InChI InChI=1S/C24H31Cl2N7O3/c25-16-6-7-17(18(26)12-16)21-31-23(36-32-21)15-8-10-33(11-9-15)19(34)13-29-22(35)20(30-24(27)28)14-4-2-1-3-5-14/h6-7,12,14-15,20H,1-5,8-11,13H2,(H,29,35)(H4,27,28,30)/t20-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Sunesis Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Concentration required to inhibit mouse interleukin-2 alpha receptor was determined by SPA assay				J Med Chem 47: 3111-30 (2004) Article DOI: 10.1021/jm049967u BindingDB Entry DOI: 10.7270/Q2TQ6280
					More data for this Ligand-Target Pair