BDBM50147988 (S)-2-[2-(2-Guanidino-acetylamino)-acetylamino]-3-(4-phenylethynyl-phenyl)-propionic acid methyl ester::CHEMBL429868

SMILES: COC(=O)[C@H](Cc1ccc(cc1)C#Cc1ccccc1)NC(=O)CNC(=O)CNC(N)=N

InChI Key: InChIKey=PZRSPVXDDCJCBQ-IBGZPJMESA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50147988   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Interleukin-2 receptor alpha chain (Mus musculus)	BDBM50147988 ((S)-2-[2-(2-Guanidino-acetylamino)-acetylamino]-3-...) Show SMILES COC(=O)[C@H](Cc1ccc(cc1)C#Cc1ccccc1)NC(=O)CNC(=O)CNC(N)=N Show InChI InChI=1S/C23H25N5O4/c1-32-22(31)19(28-21(30)15-26-20(29)14-27-23(24)25)13-18-11-9-17(10-12-18)8-7-16-5-3-2-4-6-16/h2-6,9-12,19H,13-15H2,1H3,(H,26,29)(H,28,30)(H4,24,25,27)/t19-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
Sunesis Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of mouse interleukin-2 alpha receptor by ELISA				J Med Chem 47: 3111-30 (2004) Article DOI: 10.1021/jm049967u BindingDB Entry DOI: 10.7270/Q2TQ6280
					More data for this Ligand-Target Pair