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BDBM50147996 2-[(S)-2-(4-Carbamoyl-2-guanidino-butyrylamino)-acetylamino]-3-(4-(R)-2-phenylethynyl-phenyl)-propionic acid methyl ester::CHEMBL104564

SMILES: [#6]-[#8]-[#6](=O)-[#6@H](-[#6]-c1ccc(cc1)C#Cc1ccccc1)-[#7]-[#6](=O)-[#6]-[#7]-[#6](=O)-[#6@@H](-[#6]-[#6]-[#6](-[#7])=O)\[#7]=[#6](/[#7])-[#7]

InChI Key: InChIKey=IAIDIPODDXKNFK-RTWAWAEBSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50147996   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Interleukin-2 receptor alpha chain


(Mus musculus)		BDBM50147996
PNG
(2-[(S)-2-(4-Carbamoyl-2-guanidino-butyrylamino)-ac...)
Show SMILES [#6]-[#8]-[#6](=O)-[#6@H](-[#6]-c1ccc(cc1)C#Cc1ccccc1)-[#7]-[#6](=O)-[#6]-[#7]-[#6](=O)-[#6@@H](-[#6]-[#6]-[#6](-[#7])=O)\[#7]=[#6](/[#7])-[#7]
Show InChI InChI=1S/C26H30N6O5/c1-37-25(36)21(15-19-11-9-18(10-12-19)8-7-17-5-3-2-4-6-17)31-23(34)16-30-24(35)20(32-26(28)29)13-14-22(27)33/h2-6,9-12,20-21H,13-16H2,1H3,(H2,27,33)(H,30,35)(H,31,34)(H4,28,29,32)/t20-,21+/m1/s1
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Article
PubMed
n/an/a 9.00E+5n/an/an/an/an/an/a



Sunesis Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Inhibition of mouse interleukin-2 alpha receptor by ELISA

J Med Chem 47: 3111-30 (2004)


Article DOI: 10.1021/jm049967u
BindingDB Entry DOI: 10.7270/Q2TQ6280
More data for this
Ligand-Target Pair