BDBM50148006 (S)-2-[2-((R)-3-Cyclohexyl-2-guanidino-propionylamino)-acetylamino]-3-(4-phenylethynyl-phenyl)-propionic acid methyl ester::CHEMBL108470
SMILES: [#6]-[#8]-[#6](=O)-[#6@H](-[#6]-c1ccc(cc1)C#Cc1ccccc1)-[#7]-[#6](=O)-[#6]-[#7]-[#6](=O)-[#6@@H](-[#6]-[#6]-1-[#6]-[#6]-[#6]-[#6]-[#6]-1)\[#7]=[#6](/[#7])-[#7]
InChI Key: InChIKey=MCWWAEOCNFUYJG-FTJBHMTQSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Interleukin-2 receptor alpha chain (Mus musculus) | BDBM50148006 ((S)-2-[2-((R)-3-Cyclohexyl-2-guanidino-propionylam...) | Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.70E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Sunesis Pharmaceuticals Inc. Curated by ChEMBL | Assay Description Inhibition of mouse interleukin-2 alpha receptor by ELISA | J Med Chem 47: 3111-30 (2004) Article DOI: 10.1021/jm049967u BindingDB Entry DOI: 10.7270/Q2TQ6280 | |||||||||||
More data for this Ligand-Target Pair |