BDBM50148166 4-(4-Ethoxy-pyridin-2-ylamino)-piperidine-1-carboxylic acid ethyl ester::CHEMBL112198

SMILES: CCOC(=O)N1CCC(CC1)Nc1cc(OCC)ccn1

InChI Key: InChIKey=KGIKZYZMTIMJTM-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50148166   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nitric oxide synthase, brain (Homo sapiens (Human))	BDBM50148166 (4-(4-Ethoxy-pyridin-2-ylamino)-piperidine-1-carbox...) Show SMILES CCOC(=O)N1CCC(CC1)Nc1cc(OCC)ccn1 Show InChI InChI=1S/C15H23N3O3/c1-3-20-13-5-8-16-14(11-13)17-12-6-9-18(10-7-12)15(19)21-4-2/h5,8,11-12H,3-4,6-7,9-10H2,1-2H3,(H,16,17)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Charnwood Curated by ChEMBL					Assay Description In vitro inhibition of human neuronal nitric oxide synthase.				J Med Chem 47: 3320-3 (2004) Article DOI: 10.1021/jm031035n BindingDB Entry DOI: 10.7270/Q25M656D
					More data for this Ligand-Target Pair
Nitric oxide synthase, inducible (Homo sapiens (Human))	BDBM50148166 (4-(4-Ethoxy-pyridin-2-ylamino)-piperidine-1-carbox...) Show SMILES CCOC(=O)N1CCC(CC1)Nc1cc(OCC)ccn1 Show InChI InChI=1S/C15H23N3O3/c1-3-20-13-5-8-16-14(11-13)17-12-6-9-18(10-7-12)15(19)21-4-2/h5,8,11-12H,3-4,6-7,9-10H2,1-2H3,(H,16,17)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Charnwood Curated by ChEMBL					Assay Description In vitro inhibition of human Inducible nitric oxide synthase.				J Med Chem 47: 3320-3 (2004) Article DOI: 10.1021/jm031035n BindingDB Entry DOI: 10.7270/Q25M656D
					More data for this Ligand-Target Pair
Nitric oxide synthase, endothelial (Homo sapiens (Human))	BDBM50148166 (4-(4-Ethoxy-pyridin-2-ylamino)-piperidine-1-carbox...) Show SMILES CCOC(=O)N1CCC(CC1)Nc1cc(OCC)ccn1 Show InChI InChI=1S/C15H23N3O3/c1-3-20-13-5-8-16-14(11-13)17-12-6-9-18(10-7-12)15(19)21-4-2/h5,8,11-12H,3-4,6-7,9-10H2,1-2H3,(H,16,17)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Charnwood Curated by ChEMBL					Assay Description In vitro inhibition of human endothelial nitric oxide synthase.				J Med Chem 47: 3320-3 (2004) Article DOI: 10.1021/jm031035n BindingDB Entry DOI: 10.7270/Q25M656D
					More data for this Ligand-Target Pair