BDBM50148178 CHEMBL114455::N-Benzyl-2-(2-morpholin-4-yl-3-phenyl-3,4-dihydro-quinazolin-4-yl)-acetamide::N-benzyl-2-(2-morpholino-3-phenyl-3,4-dihydroquinazolin-4-yl)acetamide

SMILES: O=C(CC1N(C(=Nc2ccccc12)N1CCOCC1)c1ccccc1)NCc1ccccc1

InChI Key: InChIKey=AOVVNXHGLKHYAS-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50148178   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Voltage-gated T-type calcium channel (Homo sapiens (Human))	BDBM50148178 (CHEMBL114455 | N-Benzyl-2-(2-morpholin-4-yl-3-phen...) Show SMILES O=C(CC1N(C(=Nc2ccccc12)N1CCOCC1)c1ccccc1)NCc1ccccc1 |c:5| Show InChI InChI=1S/C27H28N4O2/c32-26(28-20-21-9-3-1-4-10-21)19-25-23-13-7-8-14-24(23)29-27(30-15-17-33-18-16-30)31(25)22-11-5-2-6-12-22/h1-14,25H,15-20H2,(H,28,32)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.16E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Science & Technology Curated by ChEMBL					Assay Description Concentration of the compounds required for inhibition of HEK293 cells (alpha1G T-type)				Bioorg Med Chem Lett 14: 3379-84 (2004) Article DOI: 10.1016/j.bmcl.2004.04.090 BindingDB Entry DOI: 10.7270/Q21Z43VJ
					More data for this Ligand-Target Pair
Voltage-gated T-type calcium channel (Homo sapiens (Human))	BDBM50148178 (CHEMBL114455 | N-Benzyl-2-(2-morpholin-4-yl-3-phen...) Show SMILES O=C(CC1N(C(=Nc2ccccc12)N1CCOCC1)c1ccccc1)NCc1ccccc1 |c:5| Show InChI InChI=1S/C27H28N4O2/c32-26(28-20-21-9-3-1-4-10-21)19-25-23-13-7-8-14-24(23)29-27(30-15-17-33-18-16-30)31(25)22-11-5-2-6-12-22/h1-14,25H,15-20H2,(H,28,32)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.16E+4	n/a	n/a	n/a	n/a	n/a	n/a
Kyung Hee University Curated by ChEMBL					Assay Description Inhibition of human T-type calcium channel alpha1G in HEK293 cells				Bioorg Med Chem Lett 20: 38-41 (2010) Article DOI: 10.1016/j.bmcl.2009.11.049 BindingDB Entry DOI: 10.7270/Q2MS3V0M
					More data for this Ligand-Target Pair