BDBM50148200 CHEMBL114378::N-Hydroxy-2-(4-methoxy-benzenesulfonylamino)-2-methyl-propionamide

SMILES: COc1ccc(cc1)S(=O)(=O)NC(C)(C)C(=O)NO

InChI Key: InChIKey=LMSMOBVZXAUSAU-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50148200   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Interstitial collagenase (Homo sapiens (Human))	BDBM50148200 (CHEMBL114378 | N-Hydroxy-2-(4-methoxy-benzenesulfo...) Show SMILES COc1ccc(cc1)S(=O)(=O)NC(C)(C)C(=O)NO Show InChI InChI=1S/C11H16N2O5S/c1-11(2,10(14)12-15)13-19(16,17)9-6-4-8(18-3)5-7-9/h4-7,13,15H,1-3H3,(H,12,14)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibitory activity against human matrix metalloprotease-1 (MMP-1)				Bioorg Med Chem Lett 14: 3389-95 (2004) Article DOI: 10.1016/j.bmcl.2004.04.083 BindingDB Entry DOI: 10.7270/Q25Q4WPN
					More data for this Ligand-Target Pair
Collagenase 3 (Homo sapiens (Human))	BDBM50148200 (CHEMBL114378 | N-Hydroxy-2-(4-methoxy-benzenesulfo...) Show SMILES COc1ccc(cc1)S(=O)(=O)NC(C)(C)C(=O)NO Show InChI InChI=1S/C11H16N2O5S/c1-11(2,10(14)12-15)13-19(16,17)9-6-4-8(18-3)5-7-9/h4-7,13,15H,1-3H3,(H,12,14)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibitory activity against matrix metalloprotease-13 (MMP-13)				Bioorg Med Chem Lett 14: 3389-95 (2004) Article DOI: 10.1016/j.bmcl.2004.04.083 BindingDB Entry DOI: 10.7270/Q25Q4WPN
					More data for this Ligand-Target Pair