BDBM50148206 4-[4-(Naphthalen-2-yloxy)-benzenesulfonylamino]-tetrahydro-pyran-4-carboxylic acid hydroxyamide::CHEMBL325903

SMILES: ONC(=O)C1(CCOCC1)NS(=O)(=O)c1ccc(Oc2ccc3ccccc3c2)cc1

InChI Key: InChIKey=QVDLODFAOYNBNI-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50148206   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Collagenase 3 (Homo sapiens (Human))	BDBM50148206 (4-[4-(Naphthalen-2-yloxy)-benzenesulfonylamino]-te...) Show SMILES ONC(=O)C1(CCOCC1)NS(=O)(=O)c1ccc(Oc2ccc3ccccc3c2)cc1 Show InChI InChI=1S/C22H22N2O6S/c25-21(23-26)22(11-13-29-14-12-22)24-31(27,28)20-9-7-18(8-10-20)30-19-6-5-16-3-1-2-4-17(16)15-19/h1-10,15,24,26H,11-14H2,(H,23,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibitory activity against matrix metalloprotease-13 (MMP-13)				Bioorg Med Chem Lett 14: 3389-95 (2004) Article DOI: 10.1016/j.bmcl.2004.04.083 BindingDB Entry DOI: 10.7270/Q25Q4WPN
					More data for this Ligand-Target Pair
Interstitial collagenase (Homo sapiens (Human))	BDBM50148206 (4-[4-(Naphthalen-2-yloxy)-benzenesulfonylamino]-te...) Show SMILES ONC(=O)C1(CCOCC1)NS(=O)(=O)c1ccc(Oc2ccc3ccccc3c2)cc1 Show InChI InChI=1S/C22H22N2O6S/c25-21(23-26)22(11-13-29-14-12-22)24-31(27,28)20-9-7-18(8-10-20)30-19-6-5-16-3-1-2-4-17(16)15-19/h1-10,15,24,26H,11-14H2,(H,23,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibitory activity against human matrix metalloprotease-1 (MMP-1)				Bioorg Med Chem Lett 14: 3389-95 (2004) Article DOI: 10.1016/j.bmcl.2004.04.083 BindingDB Entry DOI: 10.7270/Q25Q4WPN
					More data for this Ligand-Target Pair