BDBM50148233 4-[4-(4-Fluoro-benzyloxy)-benzenesulfonylamino]-tetrahydro-pyran-4-carboxylic acid hydroxyamide::CHEMBL114528

SMILES: ONC(=O)C1(CCOCC1)NS(=O)(=O)c1ccc(OCc2ccc(F)cc2)cc1

InChI Key: InChIKey=TWXMFJCBMYOHKC-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50148233   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Collagenase 3 (Homo sapiens (Human))	BDBM50148233 (4-[4-(4-Fluoro-benzyloxy)-benzenesulfonylamino]-te...) Show SMILES ONC(=O)C1(CCOCC1)NS(=O)(=O)c1ccc(OCc2ccc(F)cc2)cc1 Show InChI InChI=1S/C19H21FN2O6S/c20-15-3-1-14(2-4-15)13-28-16-5-7-17(8-6-16)29(25,26)22-19(18(23)21-24)9-11-27-12-10-19/h1-8,22,24H,9-13H2,(H,21,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibitory activity against matrix metalloprotease-13 (MMP-13)				Bioorg Med Chem Lett 14: 3389-95 (2004) Article DOI: 10.1016/j.bmcl.2004.04.083 BindingDB Entry DOI: 10.7270/Q25Q4WPN
					More data for this Ligand-Target Pair
Interstitial collagenase (Homo sapiens (Human))	BDBM50148233 (4-[4-(4-Fluoro-benzyloxy)-benzenesulfonylamino]-te...) Show SMILES ONC(=O)C1(CCOCC1)NS(=O)(=O)c1ccc(OCc2ccc(F)cc2)cc1 Show InChI InChI=1S/C19H21FN2O6S/c20-15-3-1-14(2-4-15)13-28-16-5-7-17(8-6-16)29(25,26)22-19(18(23)21-24)9-11-27-12-10-19/h1-8,22,24H,9-13H2,(H,21,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibitory activity against human matrix metalloprotease-1 (MMP-1)				Bioorg Med Chem Lett 14: 3389-95 (2004) Article DOI: 10.1016/j.bmcl.2004.04.083 BindingDB Entry DOI: 10.7270/Q25Q4WPN
					More data for this Ligand-Target Pair