BDBM50148367 2-{(E)-3-[3,5-Bis-(4-trifluoromethyl-benzyloxy)-phenyl]-allyl}-[1,2,4]oxadiazolidine-3,5-dione::CHEMBL116136

SMILES: FC(F)(F)c1ccc(COc2cc(OCc3ccc(cc3)C(F)(F)F)cc(\C=C\Cn3oc(=O)[nH]c3=O)c2)cc1

InChI Key: InChIKey=FZZIBOOHFPOKRX-OWOJBTEDSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50148367   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tissue-type plasminogen activator (Homo sapiens (Human))	BDBM50148367 (2-{(E)-3-[3,5-Bis-(4-trifluoromethyl-benzyloxy)-ph...) Show SMILES FC(F)(F)c1ccc(COc2cc(OCc3ccc(cc3)C(F)(F)F)cc(\C=C\Cn3oc(=O)[nH]c3=O)c2)cc1 Show InChI InChI=1S/C27H20F6N2O5/c28-26(29,30)20-7-3-17(4-8-20)15-38-22-12-19(2-1-11-35-24(36)34-25(37)40-35)13-23(14-22)39-16-18-5-9-21(10-6-18)27(31,32)33/h1-10,12-14H,11,15-16H2,(H,34,36,37)/b2-1+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Invitro concentration of the compound required for inhibition of tissue type plasminogen activator by plasminogen activator inhibitor-1 at concentrat...				Bioorg Med Chem Lett 14: 3477-80 (2004) Article DOI: 10.1016/j.bmcl.2004.04.058 BindingDB Entry DOI: 10.7270/Q28C9VQ2
					More data for this Ligand-Target Pair