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SMILES: FC(F)(F)c1cccc(c1)-c1nc(cn1-c1ccnc(NC2CCCCC2)n1)C1CCNCC1

InChI Key: InChIKey=XEBPLBIKMQIKAW-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50148698   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Mitogen-activated protein kinase 14


(Mus musculus (mouse))		BDBM50148698
PNG
(CHEMBL333899 | Cyclohexyl-{4-[4-piperidin-4-yl-2-(...)
Show SMILES FC(F)(F)c1cccc(c1)-c1nc(cn1-c1ccnc(NC2CCCCC2)n1)C1CCNCC1
Show InChI InChI=1S/C25H29F3N6/c26-25(27,28)19-6-4-5-18(15-19)23-32-21(17-9-12-29-13-10-17)16-34(23)22-11-14-30-24(33-22)31-20-7-2-1-3-8-20/h4-6,11,14-17,20,29H,1-3,7-10,12-13H2,(H,30,31,33)
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n/an/a 8n/an/an/an/an/an/a



Novartis Institutes for BioMedical Research

Curated by ChEMBL


Assay Description
Inhibition of murine phosphorylated His-Mitogen-activated protein kinase p38 alpha.

Bioorg Med Chem Lett 14: 3595-9 (2004)


Article DOI: 10.1016/j.bmcl.2004.03.106
BindingDB Entry DOI: 10.7270/Q2V69J2C
More data for this
Ligand-Target Pair