BDBM50148758 2-(Quinolin-6-ylcarbamoyl)-octanedioic acid 8-hydroxyamide 1-quinolin-6-ylamide::CHEMBL327146

SMILES: ONC(=O)CCCCCC(C(=O)Nc1ccc2ncccc2c1)C(=O)Nc1ccc2ncccc2c1

InChI Key: InChIKey=RMLTYADWPTYXJV-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50148758   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50148758 (2-(Quinolin-6-ylcarbamoyl)-octanedioic acid 8-hydr...) Show SMILES ONC(=O)CCCCCC(C(=O)Nc1ccc2ncccc2c1)C(=O)Nc1ccc2ncccc2c1 Show InChI InChI=1S/C27H27N5O4/c33-25(32-36)9-3-1-2-8-22(26(34)30-20-10-12-23-18(16-20)6-4-14-28-23)27(35)31-21-11-13-24-19(17-21)7-5-15-29-24/h4-7,10-17,22,36H,1-3,8-9H2,(H,30,34)(H,31,35)(H,32,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
University of Notre Dame Curated by ChEMBL					Assay Description Inhibitory activity against human Histone deacetylase 1				J Med Chem 47: 3409-17 (2004) Article DOI: 10.1021/jm0498497 BindingDB Entry DOI: 10.7270/Q2G16085
					More data for this Ligand-Target Pair