BDBM50148847 CHEMBL3770225

SMILES: Cl.COc1ccc(F)c(Cl)c1C1CC1CN

InChI Key: InChIKey=PLYUWWSULGPEOY-UHFFFAOYSA-N

Data: 10 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50148847   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50148847 (CHEMBL3770225) Show SMILES Cl.COc1ccc(F)c(Cl)c1C1CC1CN Show InChI InChI=1S/C11H13ClFNO.ClH/c1-15-9-3-2-8(13)11(12)10(9)7-4-6(7)5-14;/h2-3,6-7H,4-5,14H2,1H3;1H	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	101	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Agonist activity at recombinant human 5HT2B receptor expressed in Flp-In-293 cells assessed as calcium flux by FLIPR assay				J Med Chem 59: 578-91 (2016) BindingDB Entry DOI: 10.7270/Q28C9Z4P
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50148847 (CHEMBL3770225) Show SMILES Cl.COc1ccc(F)c(Cl)c1C1CC1CN Show InChI InChI=1S/C11H13ClFNO.ClH/c1-15-9-3-2-8(13)11(12)10(9)7-4-6(7)5-14;/h2-3,6-7H,4-5,14H2,1H3;1H	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	119	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Agonist activity at recombinant human 5HT2A receptor expressed in Flp-In-293 cells assessed as calcium flux by FLIPR assay				J Med Chem 59: 578-91 (2016) BindingDB Entry DOI: 10.7270/Q28C9Z4P
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50148847 (CHEMBL3770225) Show SMILES Cl.COc1ccc(F)c(Cl)c1C1CC1CN Show InChI InChI=1S/C11H13ClFNO.ClH/c1-15-9-3-2-8(13)11(12)10(9)7-4-6(7)5-14;/h2-3,6-7H,4-5,14H2,1H3;1H	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	769	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Agonist activity at recombinant human 5HT2A receptor expressed in Flp-In-293 cells assessed as calcium flux by FLIPR assay				J Med Chem 59: 578-91 (2016) BindingDB Entry DOI: 10.7270/Q28C9Z4P
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50148847 (CHEMBL3770225) Show SMILES Cl.COc1ccc(F)c(Cl)c1C1CC1CN Show InChI InChI=1S/C11H13ClFNO.ClH/c1-15-9-3-2-8(13)11(12)10(9)7-4-6(7)5-14;/h2-3,6-7H,4-5,14H2,1H3;1H	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	3.20	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Agonist activity at recombinant human 5HT2C-INI receptor expressed in Flp-In-293 cells assessed as calcium flux by FLIPR assay				J Med Chem 59: 578-91 (2016) BindingDB Entry DOI: 10.7270/Q28C9Z4P
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50148847 (CHEMBL3770225) Show SMILES Cl.COc1ccc(F)c(Cl)c1C1CC1CN Show InChI InChI=1S/C11H13ClFNO.ClH/c1-15-9-3-2-8(13)11(12)10(9)7-4-6(7)5-14;/h2-3,6-7H,4-5,14H2,1H3;1H	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	776	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Agonist activity at recombinant human 5HT2A receptor expressed in Flp-In-293 cells assessed as calcium flux by FLIPR assay				J Med Chem 59: 578-91 (2016) BindingDB Entry DOI: 10.7270/Q28C9Z4P
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50148847 (CHEMBL3770225) Show SMILES Cl.COc1ccc(F)c(Cl)c1C1CC1CN Show InChI InChI=1S/C11H13ClFNO.ClH/c1-15-9-3-2-8(13)11(12)10(9)7-4-6(7)5-14;/h2-3,6-7H,4-5,14H2,1H3;1H	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	3.20	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Agonist activity at recombinant human 5HT2C-INI receptor expressed in Flp-In-293 cells assessed as calcium flux by FLIPR assay				J Med Chem 59: 578-91 (2016) BindingDB Entry DOI: 10.7270/Q28C9Z4P
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50148847 (CHEMBL3770225) Show SMILES Cl.COc1ccc(F)c(Cl)c1C1CC1CN Show InChI InChI=1S/C11H13ClFNO.ClH/c1-15-9-3-2-8(13)11(12)10(9)7-4-6(7)5-14;/h2-3,6-7H,4-5,14H2,1H3;1H	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	24	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Agonist activity at recombinant human 5HT2C-INI receptor expressed in Flp-In-293 cells assessed as calcium flux by FLIPR assay				J Med Chem 59: 578-91 (2016) BindingDB Entry DOI: 10.7270/Q28C9Z4P
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50148847 (CHEMBL3770225) Show SMILES Cl.COc1ccc(F)c(Cl)c1C1CC1CN Show InChI InChI=1S/C11H13ClFNO.ClH/c1-15-9-3-2-8(13)11(12)10(9)7-4-6(7)5-14;/h2-3,6-7H,4-5,14H2,1H3;1H	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	102	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Agonist activity at recombinant human 5HT2B receptor expressed in Flp-In-293 cells assessed as calcium flux by FLIPR assay				J Med Chem 59: 578-91 (2016) BindingDB Entry DOI: 10.7270/Q28C9Z4P
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50148847 (CHEMBL3770225) Show SMILES Cl.COc1ccc(F)c(Cl)c1C1CC1CN Show InChI InChI=1S/C11H13ClFNO.ClH/c1-15-9-3-2-8(13)11(12)10(9)7-4-6(7)5-14;/h2-3,6-7H,4-5,14H2,1H3;1H	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	120	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Agonist activity at recombinant human 5HT2A receptor expressed in Flp-In-293 cells assessed as calcium flux by FLIPR assay				J Med Chem 59: 578-91 (2016) BindingDB Entry DOI: 10.7270/Q28C9Z4P
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50148847 (CHEMBL3770225) Show SMILES Cl.COc1ccc(F)c(Cl)c1C1CC1CN Show InChI InChI=1S/C11H13ClFNO.ClH/c1-15-9-3-2-8(13)11(12)10(9)7-4-6(7)5-14;/h2-3,6-7H,4-5,14H2,1H3;1H	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	24	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Agonist activity at recombinant human 5HT2C-INI receptor expressed in Flp-In-293 cells assessed as calcium flux by FLIPR assay				J Med Chem 59: 578-91 (2016) BindingDB Entry DOI: 10.7270/Q28C9Z4P
					More data for this Ligand-Target Pair