BDBM50148850 CHEMBL3770753

SMILES: Cl.COc1cc(F)c(F)cc1C1CC1CN

InChI Key: InChIKey=ZAESISZTRUXGRX-UHFFFAOYSA-N

Data: 12 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50148850   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50148850 (CHEMBL3770753) Show SMILES Cl.COc1cc(F)c(F)cc1C1CC1CN Show InChI InChI=1S/C11H13F2NO.ClH/c1-15-11-4-10(13)9(12)3-8(11)7-2-6(7)5-14;/h3-4,6-7H,2,5,14H2,1H3;1H	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	511	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Agonist activity at recombinant human 5HT2A receptor expressed in Flp-In-293 cells assessed as calcium flux by FLIPR assay				J Med Chem 59: 578-91 (2016) BindingDB Entry DOI: 10.7270/Q28C9Z4P
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50148850 (CHEMBL3770753) Show SMILES Cl.COc1cc(F)c(F)cc1C1CC1CN Show InChI InChI=1S/C11H13F2NO.ClH/c1-15-11-4-10(13)9(12)3-8(11)7-2-6(7)5-14;/h3-4,6-7H,2,5,14H2,1H3;1H	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	81	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Agonist activity at recombinant human 5HT2A receptor expressed in Flp-In-293 cells assessed as calcium flux by FLIPR assay				J Med Chem 59: 578-91 (2016) BindingDB Entry DOI: 10.7270/Q28C9Z4P
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50148850 (CHEMBL3770753) Show SMILES Cl.COc1cc(F)c(F)cc1C1CC1CN Show InChI InChI=1S/C11H13F2NO.ClH/c1-15-11-4-10(13)9(12)3-8(11)7-2-6(7)5-14;/h3-4,6-7H,2,5,14H2,1H3;1H	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	3.20	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Agonist activity at recombinant human 5HT2C-INI receptor expressed in Flp-In-293 cells assessed as calcium flux by FLIPR assay				J Med Chem 59: 578-91 (2016) BindingDB Entry DOI: 10.7270/Q28C9Z4P
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50148850 (CHEMBL3770753) Show SMILES Cl.COc1cc(F)c(F)cc1C1CC1CN Show InChI InChI=1S/C11H13F2NO.ClH/c1-15-11-4-10(13)9(12)3-8(11)7-2-6(7)5-14;/h3-4,6-7H,2,5,14H2,1H3;1H	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	32	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Agonist activity at recombinant human 5HT2C-INI receptor expressed in Flp-In-293 cells assessed as calcium flux by FLIPR assay				J Med Chem 59: 578-91 (2016) BindingDB Entry DOI: 10.7270/Q28C9Z4P
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50148850 (CHEMBL3770753) Show SMILES Cl.COc1cc(F)c(F)cc1C1CC1CN Show InChI InChI=1S/C11H13F2NO.ClH/c1-15-11-4-10(13)9(12)3-8(11)7-2-6(7)5-14;/h3-4,6-7H,2,5,14H2,1H3;1H	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	30	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Agonist activity at recombinant human 5HT2C-INI receptor expressed in Flp-In-293 cells assessed as calcium flux by FLIPR assay				J Med Chem 59: 578-91 (2016) BindingDB Entry DOI: 10.7270/Q28C9Z4P
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50148850 (CHEMBL3770753) Show SMILES Cl.COc1cc(F)c(F)cc1C1CC1CN Show InChI InChI=1S/C11H13F2NO.ClH/c1-15-11-4-10(13)9(12)3-8(11)7-2-6(7)5-14;/h3-4,6-7H,2,5,14H2,1H3;1H	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	81	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Agonist activity at recombinant human 5HT2A receptor expressed in Flp-In-293 cells assessed as calcium flux by FLIPR assay				J Med Chem 59: 578-91 (2016) BindingDB Entry DOI: 10.7270/Q28C9Z4P
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50148850 (CHEMBL3770753) Show SMILES Cl.COc1cc(F)c(F)cc1C1CC1CN Show InChI InChI=1S/C11H13F2NO.ClH/c1-15-11-4-10(13)9(12)3-8(11)7-2-6(7)5-14;/h3-4,6-7H,2,5,14H2,1H3;1H	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	400	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Agonist activity at recombinant human 5HT2B receptor expressed in Flp-In-293 cells assessed as calcium flux by FLIPR assay				J Med Chem 59: 578-91 (2016) BindingDB Entry DOI: 10.7270/Q28C9Z4P
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50148850 (CHEMBL3770753) Show SMILES Cl.COc1cc(F)c(F)cc1C1CC1CN Show InChI InChI=1S/C11H13F2NO.ClH/c1-15-11-4-10(13)9(12)3-8(11)7-2-6(7)5-14;/h3-4,6-7H,2,5,14H2,1H3;1H	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	27	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Agonist activity at recombinant human 5HT2B receptor expressed in Flp-In-293 cells assessed as calcium flux by FLIPR assay				J Med Chem 59: 578-91 (2016) BindingDB Entry DOI: 10.7270/Q28C9Z4P
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50148850 (CHEMBL3770753) Show SMILES Cl.COc1cc(F)c(F)cc1C1CC1CN Show InChI InChI=1S/C11H13F2NO.ClH/c1-15-11-4-10(13)9(12)3-8(11)7-2-6(7)5-14;/h3-4,6-7H,2,5,14H2,1H3;1H	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	398	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Agonist activity at recombinant human 5HT2B receptor expressed in Flp-In-293 cells assessed as calcium flux by FLIPR assay				J Med Chem 59: 578-91 (2016) BindingDB Entry DOI: 10.7270/Q28C9Z4P
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50148850 (CHEMBL3770753) Show SMILES Cl.COc1cc(F)c(F)cc1C1CC1CN Show InChI InChI=1S/C11H13F2NO.ClH/c1-15-11-4-10(13)9(12)3-8(11)7-2-6(7)5-14;/h3-4,6-7H,2,5,14H2,1H3;1H	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	28	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Agonist activity at recombinant human 5HT2B receptor expressed in Flp-In-293 cells assessed as calcium flux by FLIPR assay				J Med Chem 59: 578-91 (2016) BindingDB Entry DOI: 10.7270/Q28C9Z4P
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50148850 (CHEMBL3770753) Show SMILES Cl.COc1cc(F)c(F)cc1C1CC1CN Show InChI InChI=1S/C11H13F2NO.ClH/c1-15-11-4-10(13)9(12)3-8(11)7-2-6(7)5-14;/h3-4,6-7H,2,5,14H2,1H3;1H	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	513	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Agonist activity at recombinant human 5HT2A receptor expressed in Flp-In-293 cells assessed as calcium flux by FLIPR assay				J Med Chem 59: 578-91 (2016) BindingDB Entry DOI: 10.7270/Q28C9Z4P
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50148850 (CHEMBL3770753) Show SMILES Cl.COc1cc(F)c(F)cc1C1CC1CN Show InChI InChI=1S/C11H13F2NO.ClH/c1-15-11-4-10(13)9(12)3-8(11)7-2-6(7)5-14;/h3-4,6-7H,2,5,14H2,1H3;1H	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	3.40	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Agonist activity at recombinant human 5HT2C-INI receptor expressed in Flp-In-293 cells assessed as calcium flux by FLIPR assay				J Med Chem 59: 578-91 (2016) BindingDB Entry DOI: 10.7270/Q28C9Z4P
					More data for this Ligand-Target Pair