BDBM50148861 CHEMBL3769499

SMILES: Cl.NCC1CC1c1c(F)c(F)ccc1OCC=C

InChI Key: InChIKey=YASCELUJQFTHGR-UHFFFAOYSA-N

Data: 8 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50148861   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50148861 (CHEMBL3769499) Show SMILES Cl.NCC1CC1c1c(F)c(F)ccc1OCC=C Show InChI InChI=1S/C13H15F2NO.ClH/c1-2-5-17-11-4-3-10(14)13(15)12(11)9-6-8(9)7-16;/h2-4,8-9H,1,5-7,16H2;1H	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	36	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Agonist activity at recombinant human 5HT2C-INI receptor expressed in Flp-In-293 cells assessed as calcium flux by FLIPR assay				J Med Chem 59: 578-91 (2016) BindingDB Entry DOI: 10.7270/Q28C9Z4P
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50148861 (CHEMBL3769499) Show SMILES Cl.NCC1CC1c1c(F)c(F)ccc1OCC=C Show InChI InChI=1S/C13H15F2NO.ClH/c1-2-5-17-11-4-3-10(14)13(15)12(11)9-6-8(9)7-16;/h2-4,8-9H,1,5-7,16H2;1H	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	151	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Agonist activity at recombinant human 5HT2C-INI receptor expressed in Flp-In-293 cells assessed as calcium flux by FLIPR assay				J Med Chem 59: 578-91 (2016) BindingDB Entry DOI: 10.7270/Q28C9Z4P
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50148861 (CHEMBL3769499) Show SMILES Cl.NCC1CC1c1c(F)c(F)ccc1OCC=C Show InChI InChI=1S/C13H15F2NO.ClH/c1-2-5-17-11-4-3-10(14)13(15)12(11)9-6-8(9)7-16;/h2-4,8-9H,1,5-7,16H2;1H	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	151	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Agonist activity at recombinant human 5HT2C-INI receptor expressed in Flp-In-293 cells assessed as calcium flux by FLIPR assay				J Med Chem 59: 578-91 (2016) BindingDB Entry DOI: 10.7270/Q28C9Z4P
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50148861 (CHEMBL3769499) Show SMILES Cl.NCC1CC1c1c(F)c(F)ccc1OCC=C Show InChI InChI=1S/C13H15F2NO.ClH/c1-2-5-17-11-4-3-10(14)13(15)12(11)9-6-8(9)7-16;/h2-4,8-9H,1,5-7,16H2;1H	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	3.31E+3	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Agonist activity at recombinant human 5HT2B receptor expressed in Flp-In-293 cells assessed as calcium flux by FLIPR assay				J Med Chem 59: 578-91 (2016) BindingDB Entry DOI: 10.7270/Q28C9Z4P
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50148861 (CHEMBL3769499) Show SMILES Cl.NCC1CC1c1c(F)c(F)ccc1OCC=C Show InChI InChI=1S/C13H15F2NO.ClH/c1-2-5-17-11-4-3-10(14)13(15)12(11)9-6-8(9)7-16;/h2-4,8-9H,1,5-7,16H2;1H	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	4.46E+3	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Agonist activity at recombinant human 5HT2B receptor expressed in Flp-In-293 cells assessed as calcium flux by FLIPR assay				J Med Chem 59: 578-91 (2016) BindingDB Entry DOI: 10.7270/Q28C9Z4P
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50148861 (CHEMBL3769499) Show SMILES Cl.NCC1CC1c1c(F)c(F)ccc1OCC=C Show InChI InChI=1S/C13H15F2NO.ClH/c1-2-5-17-11-4-3-10(14)13(15)12(11)9-6-8(9)7-16;/h2-4,8-9H,1,5-7,16H2;1H	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	3.34E+3	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Agonist activity at recombinant human 5HT2B receptor expressed in Flp-In-293 cells assessed as calcium flux by FLIPR assay				J Med Chem 59: 578-91 (2016) BindingDB Entry DOI: 10.7270/Q28C9Z4P
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50148861 (CHEMBL3769499) Show SMILES Cl.NCC1CC1c1c(F)c(F)ccc1OCC=C Show InChI InChI=1S/C13H15F2NO.ClH/c1-2-5-17-11-4-3-10(14)13(15)12(11)9-6-8(9)7-16;/h2-4,8-9H,1,5-7,16H2;1H	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	4.47E+3	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Agonist activity at recombinant human 5HT2B receptor expressed in Flp-In-293 cells assessed as calcium flux by FLIPR assay				J Med Chem 59: 578-91 (2016) BindingDB Entry DOI: 10.7270/Q28C9Z4P
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50148861 (CHEMBL3769499) Show SMILES Cl.NCC1CC1c1c(F)c(F)ccc1OCC=C Show InChI InChI=1S/C13H15F2NO.ClH/c1-2-5-17-11-4-3-10(14)13(15)12(11)9-6-8(9)7-16;/h2-4,8-9H,1,5-7,16H2;1H	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	36	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Agonist activity at recombinant human 5HT2C-INI receptor expressed in Flp-In-293 cells assessed as calcium flux by FLIPR assay				J Med Chem 59: 578-91 (2016) BindingDB Entry DOI: 10.7270/Q28C9Z4P
					More data for this Ligand-Target Pair