null

SMILES: CCCCN(CC)c1cc(C)nc2n(c(C)c(C)c12)-c1c(C)cc(C)cc1C

InChI Key: InChIKey=MULBKUIZDWUGKN-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50148892   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50148892 (Butyl-ethyl-[2,3,6-trimethyl-1-(2,4,6-trimethyl-ph...) Show SMILES CCCCN(CC)c1cc(C)nc2n(c(C)c(C)c12)-c1c(C)cc(C)cc1C |(15.07,3.86,;13.72,3.12,;13.67,1.59,;14.99,.78,;14.95,-.75,;16.26,-1.56,;16.21,-3.1,;13.6,-1.49,;13.55,-3.03,;12.18,-3.78,;12.13,-5.3,;10.87,-2.96,;10.92,-1.41,;9.81,-.33,;10.47,1.04,;9.75,2.4,;12.01,.83,;13.1,1.93,;12.29,-.68,;8.31,-.61,;7.3,.57,;7.84,2.02,;5.79,.3,;5.28,-1.15,;3.76,-1.42,;6.27,-2.33,;7.79,-2.06,;8.77,-3.22,)| Show InChI InChI=1S/C25H35N3/c1-9-11-12-27(10-2)22-15-19(6)26-25-23(22)20(7)21(8)28(25)24-17(4)13-16(3)14-18(24)5/h13-15H,9-12H2,1-8H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	2.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity to the cloned human corticotropin releasing factor receptor 1				Bioorg Med Chem Lett 14: 3669-73 (2004) Article DOI: 10.1016/j.bmcl.2004.05.019 BindingDB Entry DOI: 10.7270/Q2T72GWP
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50148892 (Butyl-ethyl-[2,3,6-trimethyl-1-(2,4,6-trimethyl-ph...) Show SMILES CCCCN(CC)c1cc(C)nc2n(c(C)c(C)c12)-c1c(C)cc(C)cc1C |(15.07,3.86,;13.72,3.12,;13.67,1.59,;14.99,.78,;14.95,-.75,;16.26,-1.56,;16.21,-3.1,;13.6,-1.49,;13.55,-3.03,;12.18,-3.78,;12.13,-5.3,;10.87,-2.96,;10.92,-1.41,;9.81,-.33,;10.47,1.04,;9.75,2.4,;12.01,.83,;13.1,1.93,;12.29,-.68,;8.31,-.61,;7.3,.57,;7.84,2.02,;5.79,.3,;5.28,-1.15,;3.76,-1.42,;6.27,-2.33,;7.79,-2.06,;8.77,-3.22,)| Show InChI InChI=1S/C25H35N3/c1-9-11-12-27(10-2)22-15-19(6)26-25-23(22)20(7)21(8)28(25)24-17(4)13-16(3)14-18(24)5/h13-15H,9-12H2,1-8H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	2.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity for recombinant human CRF1 receptor				Bioorg Med Chem Lett 14: 3943-7 (2004) Article DOI: 10.1016/j.bmcl.2004.05.056 BindingDB Entry DOI: 10.7270/Q2KK9B7F
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50148892 (Butyl-ethyl-[2,3,6-trimethyl-1-(2,4,6-trimethyl-ph...) Show SMILES CCCCN(CC)c1cc(C)nc2n(c(C)c(C)c12)-c1c(C)cc(C)cc1C |(15.07,3.86,;13.72,3.12,;13.67,1.59,;14.99,.78,;14.95,-.75,;16.26,-1.56,;16.21,-3.1,;13.6,-1.49,;13.55,-3.03,;12.18,-3.78,;12.13,-5.3,;10.87,-2.96,;10.92,-1.41,;9.81,-.33,;10.47,1.04,;9.75,2.4,;12.01,.83,;13.1,1.93,;12.29,-.68,;8.31,-.61,;7.3,.57,;7.84,2.02,;5.79,.3,;5.28,-1.15,;3.76,-1.42,;6.27,-2.33,;7.79,-2.06,;8.77,-3.22,)| Show InChI InChI=1S/C25H35N3/c1-9-11-12-27(10-2)22-15-19(6)26-25-23(22)20(7)21(8)28(25)24-17(4)13-16(3)14-18(24)5/h13-15H,9-12H2,1-8H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibition of CRF-stimulated cAMP production in cells expressing CRF1 receptor				Bioorg Med Chem Lett 14: 3943-7 (2004) Article DOI: 10.1016/j.bmcl.2004.05.056 BindingDB Entry DOI: 10.7270/Q2KK9B7F
					More data for this Ligand-Target Pair