BDBM50148893 CHEMBL332101::Cyclopropylmethyl-[3-(4-methoxy-phenyl)-2,5-dimethyl-3H-pyrazolo[1,5-a]pyrimidin-7-yl]-propyl-amine

SMILES: CCCN(CC1CC1)c1cc(C)nc2c(c(C)nn12)-c1ccc(OC)cc1

InChI Key: InChIKey=WMMCIPACDGGJDL-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50148893   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Corticotropin releasing factor receptor 1 (Homo sapiens (Human))	BDBM50148893 (CHEMBL332101 | Cyclopropylmethyl-[3-(4-methoxy-phe...) Show SMILES CCCN(CC1CC1)c1cc(C)nc2c(c(C)nn12)-c1ccc(OC)cc1 Show InChI InChI=1S/C22H28N4O/c1-5-12-25(14-17-6-7-17)20-13-15(2)23-22-21(16(3)24-26(20)22)18-8-10-19(27-4)11-9-18/h8-11,13,17H,5-7,12,14H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity to the cloned human corticotropin releasing factor receptor 1				Bioorg Med Chem Lett 14: 3669-73 (2004) Article DOI: 10.1016/j.bmcl.2004.05.019 BindingDB Entry DOI: 10.7270/Q2T72GWP
					More data for this Ligand-Target Pair