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SMILES: C(C1CN2CCC1CC2)c1cc2ccccc2s1

InChI Key: InChIKey=ZOGYPQAMAFELAL-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50149148   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Neuronal acetylcholine receptor subunit alpha-7


(Rattus norvegicus (Rat))		BDBM50149148
PNG
(3-Benzo[b]thiophen-2-ylmethyl-1-aza-bicyclo[2.2.2]...)
Show SMILES C(C1CN2CCC1CC2)c1cc2ccccc2s1 |(-1.18,-.17,;-2.52,-.94,;-2.52,-2.48,;-3.85,-3.26,;-5.18,-2.48,;-5.18,-.94,;-3.85,-.17,;-4.46,-1.34,;-3.4,-2.06,;-1.17,1.35,;.19,2.09,;-.09,3.6,;.85,4.83,;.26,6.25,;-1.28,6.46,;-2.21,5.23,;-1.63,3.81,;-2.29,2.42,)|
Show InChI InChI=1S/C16H19NS/c1-2-4-16-13(3-1)9-15(18-16)10-14-11-17-7-5-12(14)6-8-17/h1-4,9,12,14H,5-8,10-11H2
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Article
PubMed
n/an/a 0.110n/an/an/an/an/an/a



Mitsubishi Pharma Corporation

Curated by ChEMBL


Assay Description
Alpha 7 nicotinic acetylcholine receptor binding activity in PC12 cells

Bioorg Med Chem Lett 14: 3781-4 (2004)


Article DOI: 10.1016/j.bmcl.2004.04.091
BindingDB Entry DOI: 10.7270/Q2X066G1
More data for this
Ligand-Target Pair