BDBM50149214 CHEMBL117368::N*8*-Pyrimidin-2-yl-quinoline-2,8-diamine::N8-(pyrimidin-2-yl)quinoline-2,8-diamine

SMILES: Nc1ccc2cccc(Nc3ncccn3)c2n1

InChI Key: InChIKey=HKWYQWIBPAFXEK-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50149214   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Urokinase-type plasminogen activator (Homo sapiens (Human))	BDBM50149214 (CHEMBL117368 | N*8*-Pyrimidin-2-yl-quinoline-2,8-d...) Show SMILES Nc1ccc2cccc(Nc3ncccn3)c2n1 Show InChI InChI=1S/C13H11N5/c14-11-6-5-9-3-1-4-10(12(9)18-11)17-13-15-7-2-8-16-13/h1-8H,(H2,14,18)(H,15,16,17)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	370	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Sunesis Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Binding affinity towards Urokinase-type plasminogen activator				J Med Chem 47: 3463-82 (2004) Article DOI: 10.1021/jm040031v BindingDB Entry DOI: 10.7270/Q2NC61ZJ
					More data for this Ligand-Target Pair
Urokinase-type plasminogen activator (Homo sapiens (Human))	BDBM50149214 (CHEMBL117368 | N*8*-Pyrimidin-2-yl-quinoline-2,8-d...) Show SMILES Nc1ccc2cccc(Nc3ncccn3)c2n1 Show InChI InChI=1S/C13H11N5/c14-11-6-5-9-3-1-4-10(12(9)18-11)17-13-15-7-2-8-16-13/h1-8H,(H2,14,18)(H,15,16,17)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	2.51E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of urokinase				J Med Chem 52: 3159-65 (2009) Article DOI: 10.1021/jm801444x BindingDB Entry DOI: 10.7270/Q2FF3TM8
					More data for this Ligand-Target Pair