BDBM50149277 CHEMBL117359::[1-(4-tert-Butyl-benzyl)-5-(3-methoxy-phenyl)-1H-indol-3-yl]-oxo-acetic acid
SMILES: COc1cccc(c1)-c1ccc2n(Cc3ccc(cc3)C(C)(C)C)cc(C(=O)C(O)=O)c2c1
InChI Key: InChIKey=FKPKSNRNGMWMDA-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Plasminogen activator inhibitor-1 (Homo sapiens (Human)) | BDBM50149277 (CHEMBL117359 | [1-(4-tert-Butyl-benzyl)-5-(3-metho...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research Curated by ChEMBL | Assay Description Inhibition of human plasminogen activator inhibitor-1 | J Med Chem 47: 3491-4 (2004) Article DOI: 10.1021/jm049766q BindingDB Entry DOI: 10.7270/Q2D21X3X | |||||||||||
More data for this Ligand-Target Pair |