BDBM50149614 (E)-3-Phenyl-acrylic acid 1,3-dioxo-1,3-dihydro-isoindol-2-ylmethyl ester::CHEMBL183456

SMILES: O=C(OCN1C(=O)c2ccccc2C1=O)\C=C\c1ccccc1

InChI Key: InChIKey=NIJJDJGSTXBRTN-ZHACJKMWSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50149614   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
17-beta-hydroxysteroid-dehydrogenase (Curvularia lunata)	BDBM50149614 ((E)-3-Phenyl-acrylic acid 1,3-dioxo-1,3-dihydro-is...) Show SMILES O=C(OCN1C(=O)c2ccccc2C1=O)\C=C\c1ccccc1 Show InChI InChI=1S/C18H13NO4/c20-16(11-10-13-6-2-1-3-7-13)23-12-19-17(21)14-8-4-5-9-15(14)18(19)22/h1-11H,12H2/b11-10+	PDB MMDB B.MOAD GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Ljubljana Curated by ChEMBL					Assay Description Inhibitory activity against 17 beta-hydroxysteroid dehydrogenase catalysed oxidation reaction				Bioorg Med Chem Lett 14: 3933-6 (2004) Article DOI: 10.1016/j.bmcl.2004.05.069 BindingDB Entry DOI: 10.7270/Q2V40TN6
					More data for this Ligand-Target Pair