BDBM50149729 CHEMBL182398::{5-[1-[4-Benzyloxy-3-(4-trifluoromethyl-benzyloxy)-phenyl]-meth-(Z)-ylidene]-4-oxo-2-thioxo-thiazolidin-3-yl}-acetic acid

SMILES: OC(=O)CN1C(=S)S\C(=C/c2ccc(OCc3ccccc3)c(OCc3ccc(cc3)C(F)(F)F)c2)C1=O

InChI Key: InChIKey=OJBDRKMMPMCIEA-QRVIBDJDSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50149729   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dolichyl-phosphate-mannose--protein mannosyltransferase 1 (Candida albicans)	BDBM50149729 (CHEMBL182398 | {5-[1-[4-Benzyloxy-3-(4-trifluorome...) Show SMILES OC(=O)CN1C(=S)S\C(=C/c2ccc(OCc3ccccc3)c(OCc3ccc(cc3)C(F)(F)F)c2)C1=O Show InChI InChI=1S/C27H20F3NO5S2/c28-27(29,30)20-9-6-18(7-10-20)16-36-22-12-19(8-11-21(22)35-15-17-4-2-1-3-5-17)13-23-25(34)31(14-24(32)33)26(37)38-23/h1-13H,14-16H2,(H,32,33)/b23-13-	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
Oxfordshire OX14 4YS Curated by ChEMBL					Assay Description In vitro inhibition of Candida albicans protein mannosyl transferase 1				Bioorg Med Chem Lett 14: 3975-8 (2004) Article DOI: 10.1016/j.bmcl.2004.05.050 BindingDB Entry DOI: 10.7270/Q22J6B96
					More data for this Ligand-Target Pair