BDBM50149935 CHEMBL3769553

SMILES: CCNc1nc2cnccc2c(=O)[nH]1

InChI Key: InChIKey=VMYNUSNUYFKELK-UHFFFAOYSA-N

Data: 1 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50149935   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysine-specific demethylase 4C (Homo sapiens (Human))	BDBM50149935 (CHEMBL3769553) Show SMILES CCNc1nc2cnccc2c(=O)[nH]1 Show InChI InChI=1S/C26H28BrN5O6S/c1-2-3-14-38-26(35)31-21(25(34)32-23-13-12-19(27)15-29-23)16-30-24(33)18-10-8-17(9-11-18)20-6-4-5-7-22(20)39(28,36)37/h4-13,15,21H,2-3,14,16H2,1H3,(H,30,33)(H,31,35)(H2,28,36,37)(H,29,32,34)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.16E+3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline R&D Curated by ChEMBL					Assay Description Inhibition of N-terminal his-tagged human KDM4C expressed in Escherichia coli BL21(DE3) using trimethylated peptide substrate by RFMS assay				J Med Chem 59: 1370-87 (2016) BindingDB Entry DOI: 10.7270/Q26D5VV2
					More data for this Ligand-Target Pair